Effects of the Sugar Sucrose on Bodyweight and Energy Intake Over 28 Days in Obese Women
1 other identifier
interventional
41
0 countries
N/A
Brief Summary
This study partially replicates two previous studies with normal weight women, and overweight women. Both found that women could compensate for sucrose added to the diet in carbonated soft drinks (4 x250ml total1800 kJ per day) when it was given blind over a period of 4 weeks. The hypothesis is that this applies also to obese women, who will not gain weight, increase overall energy intake in the diet, or eat differently whilst consuming sucrose. 42 participants shall be randomly assigned to either be given carbonated drinks that contain sucrose, or drinks that are artificially sweetened.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable obesity
Started Sep 2006
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2008
CompletedFirst Submitted
Initial submission to the registry
February 22, 2013
CompletedFirst Posted
Study publicly available on registry
February 26, 2013
CompletedJanuary 28, 2016
January 1, 2016
2.1 years
February 22, 2013
January 26, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Change in body weight from baseline
4 weeks
Secondary Outcomes (1)
Mean daily dietary intake estimated from unweighed food diaries
4 weeks
Other Outcomes (1)
Rated Mood
4 weeks
Study Arms (2)
Sucrose
EXPERIMENTALReceives sucrose
Aspartame
PLACEBO COMPARATORReceives Aspartame sweetened drinks
Interventions
Eligibility Criteria
You may qualify if:
- Female
- BMI 30-35 kg/m²
- at least one period of dietary restriction of 4 weeks or more in the last 24 months
You may not qualify if:
- dislike of popular sweet carbonated drinks
- dieting during the last month
- history of diabetes
- having an eating disorder
- depression,
- being a smoker
- pregnant
- lactating,
- wearing a pacemaker
- currently taking medication for mood or thyroid disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Reid M, Hammersley R, Duffy M, Ballantyne C. Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial. Br J Nutr. 2014 Feb;111(3):563-70. doi: 10.1017/S0007114513002687. Epub 2013 Oct 29.
PMID: 24164779DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Health Psychology
Study Record Dates
First Submitted
February 22, 2013
First Posted
February 26, 2013
Study Start
September 1, 2006
Primary Completion
October 1, 2008
Study Completion
October 1, 2008
Last Updated
January 28, 2016
Record last verified: 2016-01