NCT01779661

Brief Summary

The objective of this research is to examine the effect of Infant Aquatics on the development of and neurodevelopment of preterm and near-term infants, using the GM as prognostic estimation of future development. Preterm infants, a continuously growing population, are at high risk for neurodevelopment impairments ranging from minor neurological dysfunction (MND) to cerebral palsy (CP), mainly due to developmental brain injury. Infant Aquatics have been found to benefit and promote infant development. The support and sensory stimulation of the water may improve the development the sensory, motor, as well as, autonomic system of preterm infants. The study will compare intervention by Infant Aquatics to infant massage. The intervention in both methods will start at 36 weeks gestational age for 3 months and will consist of sessions with a therapist every 2 weeks. Development will be assessed and compared at 3, 8 and 18 months using Infant Motor Pattern method, Griffith developmental scales and Vineland adaptive behavior scales.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 27, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 30, 2013

Completed
2 months until next milestone

Study Start

First participant enrolled

April 1, 2013

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
Last Updated

February 13, 2014

Status Verified

February 1, 2014

Enrollment Period

2.3 years

First QC Date

January 27, 2013

Last Update Submit

February 12, 2014

Conditions

Keywords

Neurodevelopment, Infant-Aquatics, Prematurity

Outcome Measures

Primary Outcomes (1)

  • Developmental assessment - a composite of several measures

    Developmental assessment at term and three month 1. General Movements Neuromotor scale 2. Neurological examination

    3 month

Secondary Outcomes (1)

  • Developmental assessment - a composite of several measures

    18 month

Study Arms (2)

Infant Aquatics

ACTIVE COMPARATOR
Other: Infant Aquatics

Infant Massage

ACTIVE COMPARATOR

Infant Massage

Other: Infant Massage

Interventions

Infant Aquatics in this study is composed of a set of pre-structured movements and techniques of relaxation, through harmonic integration of various approaches, each having a role in a specific time-window or in the infant's developmental sequence along study interventional timeline

Infant Aquatics

Infant Massage

Infant Massage

Eligibility Criteria

Age1 Week - 4 Weeks
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may not qualify if:

  • infants whose parents are not able to understand research goals and refuse to cooperate, infants with seizures or apnea attacks, IVH/PVH grade \>or =3, with diagnoses of chromosomal abnormalities.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chaim Seba Medical Center

Ramat Gan, 56210, Israel

RECRUITING

MeSH Terms

Conditions

Cerebral PalsyPremature Birth

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesObstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Central Study Contacts

Hagit Friedman, PhD

CONTACT

Omer Bar-Yosef, MD PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 27, 2013

First Posted

January 30, 2013

Study Start

April 1, 2013

Primary Completion

August 1, 2015

Last Updated

February 13, 2014

Record last verified: 2014-02

Locations