Effects of High Protein Intake With Intense Exercise and Energy Deficit

NCT01776359 | Completed

• 1 other identifier: REB 12-670
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

A four week intervention will take place with the participants. They will undergo 6 days a week of high intensity training. They will also be at a 40% energy deficiency. One group will have a normal intake of protein, 1.2g/kg, while the other will have 2.4g/kg. It is our thesis that the participants with the higher protein will retain more lean mass.

Conditions

Overweight

Keywords

Muscle; Protein; Diet; Exercise

Outcome Measures

Primary Outcomes (1)

• Body Composition

  To compare the effect of normal protein intake (1.2 g/kg per day) and increased protein intake (2.4 g/kg per day) on body composition over a 4 week period of energy restriction in young males (18-30), with intense exercise training. Body composition will be measured via DXA, Bod Pod, Bio-impedance, skin folds.

  4 weeks

Secondary Outcomes (1)

• Psychological state

  4 weeks

Study Arms (2)

High Protein

ACTIVE COMPARATOR

High Protein

Dietary Supplement: High Protein

Low Protein

PLACEBO COMPARATOR

Low Protein

Dietary Supplement: Low Protein

Interventions

High Protein DIETARY_SUPPLEMENT

2.4g/kg of protein

High Protein

Low Protein DIETARY_SUPPLEMENT

1.2g/kg of protein

Low Protein

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• males
• Healthy

You may not qualify if:

• more than 15% body fat
• ml/kg/min VO2
• BMI grater than 27

Sponsors & Collaborators

• McMaster University: lead

Study Sites (1)

McMaster University

Hamilton, Ontario, L8S 4L8, Canada

Location

Related Publications (4)

• Mettler S, Mitchell N, Tipton KD. Increased protein intake reduces lean body mass loss during weight loss in athletes. Med Sci Sports Exerc. 2010 Feb;42(2):326-37. doi: 10.1249/MSS.0b013e3181b2ef8e.

  PMID: 19927027 BACKGROUND

• Demling RH, DeSanti L. Effect of a hypocaloric diet, increased protein intake and resistance training on lean mass gains and fat mass loss in overweight police officers. Ann Nutr Metab. 2000;44(1):21-9. doi: 10.1159/000012817.

  PMID: 10838463 BACKGROUND

• Butterfield GE, Calloway DH. Physical activity improves protein utilization in young men. Br J Nutr. 1984 Mar;51(2):171-84. doi: 10.1079/bjn19840021.

  PMID: 6704368 BACKGROUND

• Longland TM, Oikawa SY, Mitchell CJ, Devries MC, Phillips SM. Higher compared with lower dietary protein during an energy deficit combined with intense exercise promotes greater lean mass gain and fat mass loss: a randomized trial. Am J Clin Nutr. 2016 Mar;103(3):738-46. doi: 10.3945/ajcn.115.119339. Epub 2016 Jan 27.

  PMID: 26817506 DERIVED

MeSH Terms

Conditions

Overweight; Motor Activity

Interventions

Diet, Protein-Restricted

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Diet Therapy; Nutrition Therapy; Therapeutics; Diet; Nutritional Physiological Phenomena; Diet, Food, and Nutrition; Physiological Phenomena

Study Officials

• Stuart M Phillips, PhD

  McMaster University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: January 14, 2013
• First Posted: January 28, 2013
• Study Start: February 1, 2013
• Primary Completion: July 1, 2014
• Study Completion: December 1, 2014
• Last Updated: June 9, 2015

Record last verified: 2015-06

Locations

CA (1)