NCT01766700

Brief Summary

The no calorie drink study is looking for over 300 people to participate. The study is evaluating the effect of no calorie beverages on weight loss and weight maintained over time in people who drink diet beverages every day as compared to water only drinkers during the 1 year study period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
308

participants targeted

Target at P75+ for not_applicable obesity

Timeline
Completed

Started Sep 2012

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 3, 2012

Completed
3 months until next milestone

First Posted

Study publicly available on registry

January 11, 2013

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2013

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
Last Updated

May 28, 2015

Status Verified

May 1, 2015

Enrollment Period

10 months

First QC Date

October 3, 2012

Last Update Submit

May 27, 2015

Conditions

Keywords

Obesity, weight loss, weight maintenance

Outcome Measures

Primary Outcomes (1)

  • This investigation is an equivalency trial to determine whether weight loss differs between subjects consuming beverages containing no calorie sweeteners as compared to water drinkers at 12 weeks.

    Data will be measured at 12 weeks.

Secondary Outcomes (1)

  • This investigation is an equivalency trial to determine whether weight lost and maintained during the 1 year study differs between subjects consuming beverages containing no calorie sweeteners as compared to water drinkers.

    Data will be collected at end of study.

Study Arms (2)

No calorie beverages

EXPERIMENTAL

2 no calorie beverages per day.

Behavioral: 2 no calorie beverages per day

Water

ACTIVE COMPARATOR

2 water beverages per day.

Behavioral: 2 water beverages per day

Interventions

Weekly and monthly lifestyle weight loss/maintenance classes.

Also known as: 2 non-nutritive sweetened beverages per day
No calorie beverages

Weekly and monthly lifestyle weight loss/maintenance classes.

Also known as: water only group
Water

Eligibility Criteria

Age21 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body Mass Index: 27 - 40 kg/m2
  • Must drink no calorie, sweetened drinks

You may not qualify if:

  • Cardiovascular disease
  • Uncontrolled blood pressure
  • Smoker
  • Medications that affecting metabolism
  • Oral steroids
  • History of stroke or seizures
  • Thyroid disease
  • Type 1 or 2 diabetes
  • Cushings syndrome
  • Renal disease
  • Liver disease
  • Cancer in the past 5 years
  • HIV
  • Active tuberculosis
  • Major psychiatric disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Colorado Anschutz Health and Wellness Center

Aurora, Colorado, 80022, United States

Location

Temple University

Philadelphia, Pennsylvania, 19140, United States

Location

Related Publications (1)

  • Peters JC, Wyatt HR, Foster GD, Pan Z, Wojtanowski AC, Vander Veur SS, Herring SJ, Brill C, Hill JO. The effects of water and non-nutritive sweetened beverages on weight loss during a 12-week weight loss treatment program. Obesity (Silver Spring). 2014 Jun;22(6):1415-21. doi: 10.1002/oby.20737.

MeSH Terms

Conditions

ObesityWeight Loss

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBody Weight Changes

Study Officials

  • James Hill, PhD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR
  • Gary Foster, PhD

    Temple University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2012

First Posted

January 11, 2013

Study Start

September 1, 2012

Primary Completion

July 1, 2013

Study Completion

August 1, 2014

Last Updated

May 28, 2015

Record last verified: 2015-05

Locations