Provider Notification for High B-type Natriuretic Peptide Values
Trial of Provider Notification for Patients With High B-type Natriuretic Peptide and no Imaging to Identify Unsuspected Heart Failure.
1 other identifier
interventional
115
1 country
1
Brief Summary
This proposal examines use of a clinical reminder to the primary provider of patient with a high B type natriuretic peptide but no prior imaging. Electrical Medical Record-based Intervention to Determine whether Clinical Reminders Improve Heart Failure Management in Patients with High BNP Values and Unknown LVEF.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable heart-failure
Started Oct 2010
Longer than P75 for not_applicable heart-failure
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2010
CompletedFirst Submitted
Initial submission to the registry
November 20, 2012
CompletedFirst Posted
Study publicly available on registry
November 27, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2015
CompletedSeptember 19, 2025
April 1, 2016
2.9 years
November 20, 2012
September 15, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Measurement of left ventricular ejection fraction
numerator: Measurement of left ventricular ejection fraction within 6 months of randomization. denominator: All randomized patients
6 months after randomization
Secondary Outcomes (2)
Identification of LVEF < 40%
6 months following randomizaiton
Treatment of Low LVEF
6 months following randomization
Study Arms (2)
Usual Care
NO INTERVENTIONUsual care
Clinical Reminder
EXPERIMENTALA note is sent to the primary care provider using the electronic medical record indicating the high BNP result and potential benefit of measurement of the left ventricular ejection fraction. A draft order is placed for an echocardiogram for the provider to accept or delete.
Interventions
A note is sent to the primary care provider using the electronic medical record indicating the high BNP result and potential benefit of measurement of the left ventricular ejection fraction. A draft order is placed for an echocardiogram for the provider to accept or delete.
Eligibility Criteria
You may qualify if:
- BNP \>= 200 pg/ml in last 2 months
You may not qualify if:
- Measure of LVEF in the last 12 months
- Last measure of LVEF \< 40%
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
VA Palo Alto Health Care System
Palo Alto, California, 94304, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Paul A Heidenreich, MD, MS
VA Palo Alto HCS
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- FED
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Investigator
Study Record Dates
First Submitted
November 20, 2012
First Posted
November 27, 2012
Study Start
October 1, 2010
Primary Completion
September 1, 2013
Study Completion
September 1, 2015
Last Updated
September 19, 2025
Record last verified: 2016-04