NCT01144182

Brief Summary

Heart failure (HF) greatly increases mortality and lowers quality of life (QOL). HF is the most common indication for readmission in older adults and the most frequent reason for 30-day readmission. Medications and restriction of dietary sodium constitute crucial therapy to lower HF recurrence. However, adherence to medications and dietary recommendations is low in HF patients. Nonadherence is often due to an interaction among the environment, the patient and providers. In the VALOR in Heart Failure Study, we will assess a novel quality improvement program (QIP) to improve HF care using a pretest-posttest design. This interdisciplinary theory-based prospective experimental study will target improving HF treatment using patient-based behavioral and checklist intervention, as well as provider and system-targeted checklists and treatment defaults (posttest or intervention phase); this will be compared to current best practice (CBP) evaluated in the pretest (pretest or pre-intervention) phase. It is hypothesized that the QIP, which intervenes on patient, provider and system levels, will improve QOL and lower HF recurrence compared to CBP.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
136

participants targeted

Target at P50-P75 for not_applicable heart-failure

Timeline
Completed

Started Oct 2010

Typical duration for not_applicable heart-failure

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 10, 2010

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 15, 2010

Completed
4 months until next milestone

Study Start

First participant enrolled

October 1, 2010

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2013

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2013

Completed
2.1 years until next milestone

Results Posted

Study results publicly available

October 16, 2015

Completed
Last Updated

October 16, 2015

Status Verified

August 1, 2015

Enrollment Period

2.8 years

First QC Date

June 10, 2010

Results QC Date

February 9, 2015

Last Update Submit

October 15, 2015

Conditions

Keywords

heart failurequality of lifereadmissions

Outcome Measures

Primary Outcomes (2)

  • General Quality of Life From the Standardized Physical Component Score

    Assesses General Quality of Life from VR-36, with scores ranging from 0 to 100 and higher score indicating better quality of life

    3 months after discharge

  • Heart Failure Specific Quality of Life

    Measured by Minnesota Living with Heart Failure Questionnaire. Scores range from 0-105, with higher scores indicating poorer QOL.

    3 months after discharge

Secondary Outcomes (11)

  • Standardized Mental Component Score

    3 months after discharge

  • Physical Functioning

    3 months after discharge

  • Role Physical

    3 months after discharge

  • Pain Index

    3 months after discharge

  • General Health

    3 months after discharge

  • +6 more secondary outcomes

Study Arms (2)

Current Best Practice (CBP)

NO INTERVENTION

CBP received no intervention and only current best practices for inpatient HF care.

Quality improvement program (QIP)

ACTIVE COMPARATOR

Comprehensive quality improvement program (QIP) intervenes on patient, provider and system levels. The QIP will consist of 3 monthly phone calls to promote diet and medication adherence using the transtheoretical model as a behavioral framework and checklists to facilitate patients' self-monitoring of their diet, physical activity, weight and medication taking. Further, providers during the posttest phase will use checklists for inpatient and outpatient care of HF patients.

Behavioral: Comprehensive quality improvement program (QIP)

Interventions

Comprehensive quality improvement program (QIP) that intervenes on patient, provider and system levels. The QIP will consist of 3 monthly phone calls to promote diet and medication adherence using the transtheoretical model as a behavioral framework and checklists to facilitate patients' self-monitoring of their diet, physical activity, weight and medication taking. Further, providers during the posttest phase will use checklists for inpatient and outpatient care of HF patients.

Quality improvement program (QIP)

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All patients admitted with either systolic or diastolic HF will be identified through ongoing daily prospective manual search of admission records in VA NYHHS
  • Men and women ( 21 years) being discharged after a HF admission will be eligible
  • They must have an available phone

You may not qualify if:

  • Patients with poor short-term survival (\< 3 months)
  • recent major surgery (\< 1 month)
  • planned discharge to a long-term-care facility
  • severe dementia or other serious psychiatric illness
  • temporarily in the area
  • those unable to provide consent, refusal to participate
  • logistic or discretionary reasons (including participation in another study) will be excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA New York Harbor Health Care System

New York, New York, 10010, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Results Point of Contact

Title
Sundar Natarajan, MD, M.Sc.
Organization
VA New York Harbor Healthcare System

Study Officials

  • Sundar Natarajan, MD MSc

    VA New York Harbor Health Care System

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 10, 2010

First Posted

June 15, 2010

Study Start

October 1, 2010

Primary Completion

July 1, 2013

Study Completion

September 1, 2013

Last Updated

October 16, 2015

Results First Posted

October 16, 2015

Record last verified: 2015-08

Locations