The Learning and Memory of the Experience of Pain

NCT01731314 | Completed

• 1 other identifier: 2012P002386
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the learning and memory of pain.

Conditions

Pain

Interventions

Learning and Memory of Pain BEHAVIORAL

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male and female healthy volunteers.
• years of age.
• Right-handed.
• Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

You may not qualify if:

• Any previous experience with conditioned analgesia/hyperalgesia paradigms.
• Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
• Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
• Instability of responses to experimental heat pain
• Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
• Peripheral neuropathy.

Sponsors & Collaborators

• Massachusetts General Hospital: lead

Study Sites (1)

MGH East Campus, 149 13th St.

Charlestown, Massachusetts, 02129, United States

Location

MeSH Terms

Conditions

Pain

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Socioeconomic Factors; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MS, MD

Study Record Dates

• First Submitted: November 16, 2012
• First Posted: November 21, 2012
• Study Start: January 1, 2013
• Primary Completion: January 1, 2018
• Study Completion: January 1, 2018
• Last Updated: August 13, 2019

Record last verified: 2019-08

Locations

US (1)