NCT01728103

Brief Summary

The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® and TIGRIS® Systems.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,336

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

14 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 12, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 16, 2012

Completed
2 months until next milestone

Study Start

First participant enrolled

January 1, 2013

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Last Updated

August 16, 2017

Status Verified

August 1, 2017

Enrollment Period

1.5 years

First QC Date

November 12, 2012

Last Update Submit

August 14, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Qualitative detection of ribosomal RNA from Chlamydia trachomatis and/or Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) to aid in the diagnosis of chlamydial and/or gonococcal and/or trichomonal urogenital disease

    approximately one year

Study Arms (1)

No Treatment

Device: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays

Interventions

In Vitro Diagnostic Assays

No Treatment

Eligibility Criteria

Age16 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Female subjects at least 16 years of age, with or without symptoms of sexually transmitted disease.

You may qualify if:

  • The subject is at least 16 years of age at the time of enrollment and is currently sexually active (has had penile/vaginal intercourse within the past 12 months)
  • The subject and/or legally authorized representative is willing to undergo the informed consent process prior to study participation (a minor will need the documented consent of his/her parent or legal guardian, unless the site has an institutional review board \[IRB\]-approved waiver for parental consent for minors)
  • In addition, the subject must meet at least one of the following criteria:
  • The subject reports symptoms consistent with a suspected sexually transmissible infection (STI) such as abnormal discharge, genital itching, pain/discomfort during sexual intercourse or urination, and/or lower abdominal discomfort
  • Subject is asymptomatic and known to be partners with, or a contact of, a person with a confirmed or suspected STI(s)
  • Subject is asymptomatic and undergoing screening evaluation for possible STIs
  • Subject is asymptomatic and undergoing a routine examination with a pelvic examination

You may not qualify if:

  • The subject took antibiotic medications within the last 21 days
  • Subject already participated in this study
  • Subject has a history of illness that the principal investigator (PI) or designee considers could interfere with or affect the conduct, results, and/or completion of the clinical trial
  • Subject has a history of illness that the PI or designee considers could create an unacceptable risk to the subject if enrolled

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (14)

Infectious Diseases STD Program University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States

Location

Medical Center for Clinical Research

San Diego, California, 92108, United States

Location

Healthcare Clinical Data

North Miami, Florida, 33161, United States

Location

Mount Vernon Clinical Research

Sandy Springs, Georgia, 30328, United States

Location

Louisiana State University Health Sciences Center Dept. of Medicine, Infectious Disease

New Orleans, Louisiana, 70112, United States

Location

John Hopkins University

Baltimore, Maryland, 21205, United States

Location

New England Center for Clinical Research

Fall River, Massachusetts, 02720, United States

Location

University of North Carolina Chapel Hill

Chapel Hill, North Carolina, 27599-7030, United States

Location

Cincinnati Children's Hospital Medical Center Division of Pediatric & Adolescent Gynecology

Cincinnati, Ohio, 45229-3039, United States

Location

Planned Parenthood Southeastern Pennsylvania

Philadelphia, Pennsylvania, 19107, United States

Location

Medical University of South Carolina

Charleston, South Carolina, 29425, United States

Location

The Jackson Clinic

Jackson, Tennessee, 38305, United States

Location

Planned Parenthood Gulf Coast

Houston, Texas, 77023, United States

Location

Tidewater Clinical Research

Norfolk, Virginia, 23502, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

urine; endocervical and vaginal swabs

MeSH Terms

Conditions

Chlamydia InfectionsGonorrheaTrichomonas Infections

Condition Hierarchy (Ancestors)

Chlamydiaceae InfectionsGram-Negative Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsSexually Transmitted Diseases, BacterialSexually Transmitted DiseasesCommunicable DiseasesGenital DiseasesUrogenital DiseasesNeisseriaceae InfectionsProtozoan InfectionsParasitic Diseases

Study Officials

  • Renee Wait

    Gen-Probe, Incorporated

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 12, 2012

First Posted

November 16, 2012

Study Start

January 1, 2013

Primary Completion

July 1, 2014

Last Updated

August 16, 2017

Record last verified: 2017-08

Locations