NCT01638637

Brief Summary

The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs and male first-catch urine and urethral swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® System

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,492

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2012

Geographic Reach
1 country

16 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2012

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

February 29, 2012

Completed
4 months until next milestone

First Posted

Study publicly available on registry

July 12, 2012

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2013

Completed
Last Updated

October 17, 2013

Status Verified

October 1, 2013

Enrollment Period

1.3 years

First QC Date

February 29, 2012

Last Update Submit

October 16, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Qualitative detection of ribosomal RNA from Chlamydia trachomatis and/or Neisseria gonorrhoeae (GC) to aid in the diagnosis of chlamydial and/or gonococcal urogenital disease

    approximately one year

Study Arms (1)

Specimen Collection

Device: APTIMA Assays; PANTHER System

Interventions

APTIMA Assays; PANTHER System

Also known as: APTIMA Combo, APTIMA CT, APTIMA GC
Specimen Collection

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Symptomatic and asymptomatic subjects at least 16 years of age.

You may qualify if:

  • The subject is at least 16 years of age at the time of enrollment and is currently sexually active (has had intercourse within the past 12 months)
  • The subject and/or legally authorized representative is willing to undergo the informed consent process prior to study participation (a minor will need the documented consent of his/her parent or legal guardian, unless the site has an institutional review board (IRB)-approved waiver for parental consent for minors)
  • In addition, the subject must meet at least one of the following criteria:
  • The subject reports symptoms consistent with a suspected STI such as abnormal discharge, genital itching, pain/discomfort during sexual intercourse or urination, and/or lower abdominal discomfort
  • Subject is asymptomatic and known to be partners with, or a contact of, a person with a confirmed or suspected STI(s)
  • Subject is asymptomatic and undergoing screening evaluation for possible STIs
  • Subject (female) is asymptomatic and undergoing a routine examination with a pelvic examination

You may not qualify if:

  • A potential subject will be ineligible for clinical trial enrollment if the subject, clinician, or medical record reports any of the following:
  • The subject took antibiotic medications within the last 21 days
  • Subject already participated in this study
  • Subject has a history of illness that the principal investigator (PI) or designee considers could interfere with or affect the conduct, results, and/or completion of the clinical trial
  • Subject has a history of illness that the PI or designee considers could create an unacceptable risk to the subject if enrolled

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (16)

University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States

Location

Anthony Mills MD Inc.

Los Angeles, California, 90069, United States

Location

Benchmark Research

San Francisco, California, 94102, United States

Location

Planned Parenthood Southern New England

New Haven, Connecticut, 06511, United States

Location

AGA Clinical Trials

Hialeah, Florida, 33012, United States

Location

Wishard Health Services

Indianapolis, Indiana, 46202, United States

Location

Louisiana State University Health Sciences

New Orleans, Louisiana, 70112, United States

Location

John Hopkins University

Baltimore, Maryland, 21205, United States

Location

New England Center for Clinical Research - New Bedford Clinic

New Bedford, Massachusetts, 02744, United States

Location

Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States

Location

Laboratory Corporation of America

Burlington, North Carolina, 27215, United States

Location

University of North Carolina Chapel Hill

Chapel Hill, North Carolina, 27599-7030, United States

Location

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229-3039, United States

Location

Molecular Pathology Laboratory Network, Inc.

Maryville, Tennessee, 37804, United States

Location

Planned Parenthood Houston and Southeast Texas

Houston, Texas, 77023, United States

Location

Tidewater Clinical Research, Inc. -Tidewater Physicians for Women

Norfolk, Virginia, 23502, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

urine

MeSH Terms

Conditions

Chlamydia InfectionsGonorrhea

Condition Hierarchy (Ancestors)

Chlamydiaceae InfectionsGram-Negative Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsSexually Transmitted Diseases, BacterialSexually Transmitted DiseasesCommunicable DiseasesGenital DiseasesUrogenital DiseasesNeisseriaceae Infections

Study Officials

  • Jennifer Reid, PhD

    Gen-Probe, Incorporated

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 29, 2012

First Posted

July 12, 2012

Study Start

February 1, 2012

Primary Completion

June 1, 2013

Study Completion

July 1, 2013

Last Updated

October 17, 2013

Record last verified: 2013-10

Locations