NCT01672281

Brief Summary

In endurance sports competitions such as cycling, an athlete's capacity to sustain submaximum power (i.e. endurance capacity) strongly influences overall race performance. Endurance capacity can be increased by both long, continuous endurance exercise at moderate oxygen consumption, and high-intensity (at or above peak oxygen consumption) interval training. However, it has also been shown that resistance exercise, if performed in addition to endurance exercise, can further enhance endurance capacity. The investigators have recently described a novel training method, which is based on combined vibration and resistance training and superimposed vascular occlusion. Based on the investigators previous results showing that this type of training leads to marked increases in endurance capacity in previously untrained young women, the investigators aim at investigating whether the method is also effective in increasing endurance capacity in highly endurance-trained young men, and whether the method leads to bigger improvements relative to resistance exercise alone. Besides the functional outcomes the investigators are also interested in the specificity of the cellular adaptations with respect to the two trainings methods.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

May 25, 2012

Completed
3 months until next milestone

First Posted

Study publicly available on registry

August 24, 2012

Completed
8 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

May 14, 2013

Status Verified

May 1, 2013

Enrollment Period

10 months

First QC Date

May 25, 2012

Last Update Submit

May 13, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in Critical Power

    The difference in changes in Critical Power \[Watts\] are compared between the vibrox- and resistance training group. For this purpose, participants complete pre and post training a cycling ramp test and 4 cycling constant load tests.

    2 month intervention

Study Arms (2)

vibrox training

EXPERIMENTAL
Other: vibrox- vs. resistance training

resistance training

EXPERIMENTAL
Other: vibrox- vs. resistance training

Interventions

Comparison between two exercise interventions

Also known as: vibrox
resistance trainingvibrox training

Eligibility Criteria

Age18 Years - 35 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • male
  • no fever / no common cold at the beginning of the study
  • at least 4 endurance training sessions prior to beginning of study
  • age 18-35y
  • non-smoker
  • no cardiological / orthopedic problems
  • no pacemaker
  • fulfills health questionnaire's requirements

You may not qualify if:

  • fever / common cold at beginning of study
  • untrained condition (less than 4 endurance training sessions prior to the
  • beginning of the study)
  • age under 18 oder above 35y
  • smoker
  • cardiovascular or orthopedic problems
  • cardiac pacemaker
  • does not fulfill health questionnaire's requirements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich, Division of Neurology

Zurich, Canton of Zurich, 8091 Zurich, Switzerland

Location

Related Publications (1)

  • Mueller SM, Aguayo D, Lunardi F, Ruoss S, Boutellier U, Frese S, Petersen JA, Jung HH, Toigo M. High-load resistance exercise with superimposed vibration and vascular occlusion increases critical power, capillaries and lean mass in endurance-trained men. Eur J Appl Physiol. 2014 Jan;114(1):123-33. doi: 10.1007/s00421-013-2752-2. Epub 2013 Oct 24.

MeSH Terms

Conditions

Health Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Hans H. Jung, Professor MD

    University Hospital Zurich, Division of Neurology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 25, 2012

First Posted

August 24, 2012

Study Start

November 1, 2011

Primary Completion

September 1, 2012

Study Completion

December 1, 2012

Last Updated

May 14, 2013

Record last verified: 2013-05

Locations