Course of Obesity and Extreme Obesity in Adolescents
YES
YES
Sponsor study identifier
Secondary identifiers
REGISTRY · Deutsches Register Klinischer Studien
OTHER_GRANT · Bundesministerium für Bildung und Forschung
observational
429
1 country
5
Study Start
July 2012
Actual (reported)Primary Completion
July 2023
Actual (reported)Study Completion
July 2023
Actual (reported)The rate of adolescent extreme obesity is rapidly rising, and impacting quality of life, psychosocial situation, and health of the affected youth. However, as few of these adolescents seek medical care, little is known about the longitudinal course of adolescent extreme obesity. In this study, the investigators aim to provide structured care for adolescents with obesity and extreme obesity over a prolonged period of time, and to gain information on the course of obesity and the success of different treatment options. The study is a subproject of the "Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care", short: "Youth with Extreme obesity Study (YES)", which aims at improving the medical care and social support structures for youth with obesity and extreme obesity in Germany. Obese youth and young adults (BMI ≥ 30kg/m2) between the ages of 14 and 24.9 years (initially up to 21 years) are eligible to participate. Participants will have a physical check-up every 12 months (initially every 6 months), complete questionnaires on their health, socioeconomic status and wellbeing, and are offered blood test and diagnostic procedures to assess comorbidities. Participants are offered support and guidance for social and vocational integration. The study will evaluate and inform treatment and support options for adolescents with extreme obesity.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 2023
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2012
Actual (reported)July 20, 2012
Actual (reported)August 10, 2012
Actual (reported)July 2023
Actual (reported)July 2023
Actual (reported)adherence with structured care
The percentage of subjects that comply with the structured follow up program will be calculated once a year.
12 months after subject inclusion
percentage of subjects that can be integrated into the job-market or into an apprenticeship training position
every 12 months for 9 years
percentage of subjects that undergo the recommended diagnostic procedures
every 12 months for 9 years
changes in somatic co-morbidities
every 12 months for 9 years
changes in psychiatric co-morbidities
every 12 months for 9 years
compliance with treatment of somatic co-morbidities
every 12 months for 9 years
BMI ≥35kg/m2
BMI 30-34.9kg/m2
Subjects will be recruited from the general population through different healthcare- and non healthcare settings to ascertain the inclusion of treatment-seeking and non treatment-seeking individuals. Healthcare settings include university based obesity clinics, physician offices and health insurance agencies. Non-healthcare settings include schools, job centers, and employment agencies.
Ambulatory Obesity Program, Charité University, Berlin
Berlin, 13353, Germany
Vestische Kinderklinik, University of Witten/Herdecke
Datteln, Germany
University Duisburg-Essen
Essen, 45147, Germany
University Hospital Leipzig
Leipzig, 04103, Germany
Dept for Pediatrics and Adolescent Medicine, University of Ulm: Interdisciplinary obesity clinic
Ulm, 89075, Germany
Wabitsch M, Moss A, Reinehr T, Wiegand S, Kiess W, Scherag A, Holl R, Holle R, Hebebrand J. Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care, short: Youth with Extreme Obesity Study (YES). BMC Public Health. 2013 Aug 29;13:789. doi: 10.1186/1471-2458-13-789.
Samples of fasting plasma, serum, DNA, and urine will be retained.
Martin Wabitsch, Prof. Dr. med.
University of Ulm
Susanna Wiegand, Dr. med.
Charite University, Berlin, Germany
Thomas Reinehr, Prof. Dr. med.
University of Witten/Herdecke
Johannes Hebebrand, Prof. Dr. med.
Universität Duisburg-Essen
429 participants (actual enrollment reported by the registry).
First Submitted
July 20, 2012
First Posted
August 10, 2012
Study Start
July 2012
Actual (reported)Structured Psychoeducation for Unemployed Adolescents With Extreme Obesity in a Multicenter Observational Study Focusing on Feasibility
Contact the study team to confirm eligibility.
Wieland Kiess, Prof. Dr. med.
University of Leipzig
Reinhard Holl, Prof. Dr. med.
University of Ulm
Primary Completion
July 2023
Actual (reported)Study Completion
July 2023
Actual (reported)Last Updated
May 8, 2024
Record last verified: 2024-05
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Source: ClinicalTrials.gov.
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