Economic Aspects of Extreme Obesity in Adolescent

NCT01632098 | Completed DMC

• 4 other identifiers: U1111-1131-4384dDRKS0000419701GI1127U1111-1131-8145
• Study Type: observational
• Target: 429
• Locations: 1 country
• Sites: 5

Brief Summary

Obesity is one of the biggest public health challenges today and in the years to come, particularly due to its rising prevalence in children and adolescents. In addition to the increased health risks for each individual, obesity causes a tremendous economic burden on the healthcare system. Here, the investigators will examine the impact of extreme obesity on healthcare utilization, costs, and health related quality of life in adolescents. The study is a subproject of the "Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care study", short: "Youth with Extreme obesity Study (YES)", which aims at improving the medical care and social support structures for youth with obesity and extreme obesity in Germany. Obese youth and young adults (BMI ≥ 30kg/m2) between the ages of 14 and 24.9 years (initially up to 21 years) are eligible to participate. Participants will complete questionnaires to assess health related quality of life and utilization of healthcare. These questionnaires will be applied at baseline and then every 12 months (initially every 6 months) during health check-ups. As part of the other subprojects of YES, participants will be invited to complete further questionnaires and will be offered a thorough medical examination, medical care and psycho-social support. The investigators expect to provide valid and up-to-date information on costs and health-related quality of life for obese adolescents. This information will help in the planning of useful and cost effective preventive and therapeutic strategies, and improve the medical care and support structures for obese adolescents.

Conditions

Obesity; Extreme Obesity

Keywords

psychosocial; healthcare; co-morbidities; extremely obese adolescents

Outcome Measures

Primary Outcomes (1)

• Economic burden of extreme obesity in adolescents living in Germany

  Resource utilization and calculate health care cost will be elicited using a standardized patient questionnaire that was developed and tested by the Helmholtz Zentrum München.

  baseline

Secondary Outcomes (3)

• Health related quality of life associated with extreme obesity in adolescents

  at baseline and every 12 months

• BMI

  at baseline and every 12 months

• Changes in economic burden of extreme obesity in adolescents living in Germany

  every 12 months

Study Arms (2)

extremely obese

BMI ≥35kg/m2

obese

BMI 30-34.9kg/m2

Eligibility Criteria

• Age: 14 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Subjects will be recruited from the general population through different healthcare- and non healthcare settings to ascertain the inclusion of treatment-seeking and non treatment-seeking individuals. Healthcare settings include university based obesity clinics, physician offices and health insurance agencies. Non-healthcare settings include schools, job centers, and employment agencies.

You may qualify if:

• BMI ≥30kg/m2
• sufficient German language skills

You may not qualify if:

• none

Sponsors & Collaborators

• University of Ulm: lead
• University of Witten/Herdecke: collaborator
• Charite University, Berlin, Germany: collaborator
• University of Leipzig: collaborator
• Universität Duisburg-Essen: collaborator
• Helmholtz Zentrum München: collaborator

Study Sites (5)

Ambulatory Obesity Program, Charité University, Berlin

Berlin, 13353, Germany

Location

Vestische Kinderklinik, University of Witten/Herdecke

Datteln, Germany

Location

University Duisburg-Essen

Essen, 45147, Germany

Location

University Hospital Leipzig

Leipzig, 04103, Germany

Location

Dept for Pediatrics and Adolescent Medicine, University of Ulm: Interdisciplinary obesity clinic

Ulm, 89075, Germany

Location

Related Publications (1)

• Wabitsch M, Moss A, Reinehr T, Wiegand S, Kiess W, Scherag A, Holl R, Holle R, Hebebrand J. Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care, short: Youth with Extreme Obesity Study (YES). BMC Public Health. 2013 Aug 29;13:789. doi: 10.1186/1471-2458-13-789.

  PMID: 23987123 DERIVED

Related Links

• study homepage

MeSH Terms

Conditions

Obesity; Obesity, Morbid

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Martin Wabitsch, Prof. Dr. med.

  University of Ulm

  PRINCIPAL INVESTIGATOR

• Susanna Wiegand, Dr. med.

  Charite University, Berlin, Germany

  PRINCIPAL INVESTIGATOR

• Thomas Reinehr, Prof. Dr. med.

  University of Witten/Herdecke

  PRINCIPAL INVESTIGATOR

• Johannes Hebebrand, Prof. Dr. med.

  Universität Duisburg-Essen

  PRINCIPAL INVESTIGATOR

• Wieland Kiess, Prof. Dr. med.

  University of Leipzig

  PRINCIPAL INVESTIGATOR

• Reinhard Holl, Prof. Dr. med.

  University of Ulm

  PRINCIPAL INVESTIGATOR

• Rolf Holle, Prof. Dr.

  Helmholz Center Munich

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Division Chief Pediatric Endocrinology and Diabetology

Study Record Dates

• First Submitted: June 22, 2012
• First Posted: June 29, 2012
• Study Start: July 1, 2012
• Primary Completion: July 1, 2023
• Study Completion: July 1, 2023
• Last Updated: May 8, 2024

Record last verified: 2024-05

Locations

DE (5)