NCT01647438

Brief Summary

Translating a Heart Disease Lifestyle Intervention in the Community study will evaluate the feasibility and initial effectiveness of a community-based, culturally-targeted, lifestyle intervention to improve the cardiovascular health of underserved South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) Americans. Participants in this study will be randomly assigned to either a group to receive heart disease prevention classes or to another group where they will receive written materials about heart disease prevention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
63

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Aug 2012

Typical duration for not_applicable obesity

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 19, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 23, 2012

Completed
9 days until next milestone

Study Start

First participant enrolled

August 1, 2012

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2015

Completed
9 months until next milestone

Results Posted

Study results publicly available

November 2, 2015

Completed
Last Updated

November 2, 2015

Status Verified

October 1, 2015

Enrollment Period

1.3 years

First QC Date

July 19, 2012

Results QC Date

July 17, 2015

Last Update Submit

October 1, 2015

Conditions

Keywords

South AsiansDiabetesPhysical ActivityCoronary Heart DiseaseLifestyle

Outcome Measures

Primary Outcomes (2)

  • Change in Physical Activity (Minutes/Week)

    Change from baseline in minutes per week of physical activity measured by accelerometer at 6-months.

    baseline and 6-months

  • Change in Saturated Fat (% of Daily Kilo-calories From Fat) Intake

    Change from baseline in saturated fat (% of daily kilo-calories from fat) intake measured by 24-hour food recall at 6-months

    baseline and 6-months

Study Arms (2)

Print Health Education

OTHER

Participants receive print health education materials

Other: Print Health Education

Lifestyle Intervention

EXPERIMENTAL

Six weekly health education classes and phone counseling.

Behavioral: Lifestyle Intervention

Interventions

Participants will enroll in heart disease prevention group sessions focusing on physical activity, diet, weight, and stress management. Each group will have 6 to 8 participants who will attend 6 weekly, 90 minute group education sessions at Metropolitan Asian Family Services. During each session, participants will watch videos on the day's topic followed by discussion, activities, and assistance in setting realistic goals with attention to physical activity, diet, weight, and stress management. Participants will receive telephone support after each session and up to 12 weeks after they have completed the classes to help reinforce learning objectives.

Lifestyle Intervention

Participants will receive primary care referrals and print health education material about heart disease prevention in the mail.

Print Health Education

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • South Asians between 30 and 60 years
  • Have at least one CHD risk factor: obesity (body mass index \> 25 kg/m2- cutoff for obesity in South Asians), hyperlipidemia, hypertension, pre-diabetes, or diabetes.

You may not qualify if:

  • Inability to speak English, Hindi, or Urdu
  • History of clinically evident CVD (e.g. heart attack, stroke)
  • Pregnant, lactating, or planning to become pregnant during the study period
  • Conditions that inhibit moderate intensity physical activity
  • Systolic blood pressure ≥190 or diastolic blood pressure ≥105; Triglycerides ≥ 400
  • Using insulin for diabetes
  • Significant medical or psychiatric co-morbidities
  • Plans to move out of the area within 2 years
  • Family/household member enrolled in study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Northwestern University-Feinberg School of Medicine

Chicago, Illinois, 60611, United States

Location

Metropolitan Asian Family Services

Chicago, Illinois, 60645, United States

Location

Related Publications (3)

  • Jayaprakash M, Puri-Taneja A, Kandula NR, Bharucha H, Kumar S, Dave SS. Qualitative Process Evaluation of a Community-Based Culturally Tailored Lifestyle Intervention for Underserved South Asians. Health Promot Pract. 2016 Nov;17(6):802-813. doi: 10.1177/1524839916650165. Epub 2016 May 24.

  • Kandula NR, Dave S, De Chavez PJ, Bharucha H, Patel Y, Seguil P, Kumar S, Baker DW, Spring B, Siddique J. Translating a heart disease lifestyle intervention into the community: the South Asian Heart Lifestyle Intervention (SAHELI) study; a randomized control trial. BMC Public Health. 2015 Oct 16;15:1064. doi: 10.1186/s12889-015-2401-2.

  • Kandula NR, Patel Y, Dave S, Seguil P, Kumar S, Baker DW, Spring B, Siddique J. The South Asian Heart Lifestyle Intervention (SAHELI) study to improve cardiovascular risk factors in a community setting: design and methods. Contemp Clin Trials. 2013 Nov;36(2):479-87. doi: 10.1016/j.cct.2013.09.007. Epub 2013 Sep 21.

MeSH Terms

Conditions

ObesityHyperlipidemiasHypertensionGlucose IntoleranceDiabetes MellitusMotor ActivityCoronary Disease

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsDyslipidemiasLipid Metabolism DisordersMetabolic DiseasesVascular DiseasesCardiovascular DiseasesHyperglycemiaGlucose Metabolism DisordersEndocrine System DiseasesBehaviorMyocardial IschemiaHeart Diseases

Results Point of Contact

Title
Dr. Namratha Kandula, Principal Investigator
Organization
Northwestern University

Study Officials

  • Namratha Kandula, MD, MPH

    Northwestern University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Namratha Kandula, MD, MPH

Study Record Dates

First Submitted

July 19, 2012

First Posted

July 23, 2012

Study Start

August 1, 2012

Primary Completion

December 1, 2013

Study Completion

February 1, 2015

Last Updated

November 2, 2015

Results First Posted

November 2, 2015

Record last verified: 2015-10

Locations