Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

NCT01608152 | Recruiting

• 3 other identifiers: 2012-0362NCI-2020-00573R41CA168107
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This trial collects feedback from patients to develop a video game in improving the outcomes in stem cell transplant survivors. A video game may help to improve health behaviors for leukemia or lymphoma patients after stem cell transplant.

Conditions

Leukemia; Lymphoma

Keywords

Leukemia; Lymphoma; Game mechanics; Stem cell transplant survivors; Hematopoietic stem cell transplantation; HSCT; Internet-based; Interactive and personalized intervention; Questionnaires; Focus groups; Interviews

Outcome Measures

Primary Outcomes (1)

• Feasibility of electronic game intervention

  Primary feasibility benchmark based on responses to questions regarding users' perceptions of the technology. If 75% of respondents have a mean score reflecting positive responses (e.g., strongly agree or agree) to each of the 7 constructs related to users' perceptions, as described above, then feasibility benchmark met. Responses to open-ended questions analyzed qualitatively using Atlas.ti software. Responses to individual questions evaluated to look for common themes, and findings used to inform future development of the prototype.

  4 weeks

Study Arms (2)

Group I (focus group)

Patients attend a focus group for up to 1.5 hours and provide feedback on design elements, specific desirable features, and preferences for the initial prototype.

Behavioral: Focus Group

Group II (access to the game)

Patients have access to the game for 3 weeks and then provide feedback on problems or questions regarding the use of the prototype.

Other: Internet-Based Intervention; Behavioral: Interview

Interventions

Focus Group BEHAVIORAL

Attend a focus group

Group I (focus group)

Internet-Based Intervention OTHER

Have access to the game

Group II (access to the game)

Interview BEHAVIORAL

1 week after the 3-week period ends, interview conducted over the phone or at a clinic visit.

Group II (access to the game)

Eligibility Criteria

• Age: 15 Years - 39 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients with leukemia or lymphoma

You may qualify if:

• Phase I
• The target population for this study will consist of:
• Individuals ages 15-29
• Able to read and speak English
• Diagnosis of leukemia or lymphoma
• First time allogeneic SCT recipient
• Phase II
• The target population for this study will consist of:
• Individuals ages 18-39 (in phase I, we recruited only individuals age 15-29. For phase II, we will recruit young adults, and will expand the eligible age range up to 39 years. This expansion in age eligibility to 39 years is consistent with the National Cancer Institute definition of adolescents and young adults with cancer, and is consistent with the age range of patients seen at MD Anderson in the Adolescent and Young Adult Center.
• Able to read and speak English
• Diagnosis of leukemia or lymphoma (including Myelodysplastic Syndrome - MDS) or lymphoma
• HSCT recipient

You may not qualify if:

• Phase I
• The target population will be excluded if:
• They do not speak English
• They have vision problems
• They have cognitive problems
• They have psychological difficulties
• Phase II
• The target population will be excluded if:
• They do not speak English
• They have vision problems that would preclude them from viewing a computer screen.
• They have an intellectual deficiency that would prevent the potential participant from understanding information delivered on the computer platform or as defined by the DSM-V Diagnostic and Statistical Manual of Mental Disorders that would prevent them from understanding information delivered on the computer platform.

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• MD Anderson Cancer Center

MeSH Terms

Conditions

Leukemia; Lymphoma

Interventions

Focus Groups; Interviews as Topic

Condition Hierarchy (Ancestors)

Neoplasms by Histologic Type; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases; Lymphoproliferative Disorders; Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Susan K Peterson

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Susan Peterson, MPH,PhD

CONTACT

713-792-8267; speterso@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 25, 2012
• First Posted: May 30, 2012
• Study Start: February 20, 2013
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: October 27, 2025

Record last verified: 2025-10

Locations

US (1)