NCT01584778

Brief Summary

Eosinophil cationic protein (ECP) is a matrix protein of eosinophils and has been reported to reflect eosinophil activity. Few studies have examined the role of eosinophils in the pathogenesis of Behçet's disease. The purpose of the present study is to investigate the serum ECP levels in BD and its relation to clinical activity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
47

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2002

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2002

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2002

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2002

Completed
9.4 years until next milestone

First Submitted

Initial submission to the registry

April 24, 2012

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 25, 2012

Completed
Last Updated

April 26, 2012

Status Verified

April 1, 2012

Enrollment Period

11 months

First QC Date

April 24, 2012

Last Update Submit

April 25, 2012

Conditions

Behçet's Disease

Keywords

Behçet's diseaseEosinophil cationic proteinEosinophils

Study Arms (3)

Behçet patients

Other: eosinophil cationic protein

Healthy controls

Other: eosinophil cationic protein

Allergic rhinitis (diseased) controls

Other: eosinophil cationic protein

Interventions

eosinophil cationic proteinOTHER

Serum eosinophil cationic protein levels

Also known as: ECP
Allergic rhinitis (diseased) controlsBehçet patientsHealthy controls

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Consecutive Behçet patients of the outpatient clinic of the Rheumatology-Immunology Department of University Hospital

You may qualify if:

  • Consecutive Behçet patients who gave the written informed consent were included.

You may not qualify if:

  • Patients on corticosteroids or immunosuppressives were excluded.Cases with any allergy history or parasitosis were excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cukurova University, Faculty of Medicine, Rheumatology-Immunology Department

Adana, 01330, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Behcet Syndrome

Interventions

Eosinophil Cationic Protein

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic DiseasesUveitis, AnteriorPanuveitisUveitisUveal DiseasesEye DiseasesVasculitisVascular DiseasesCardiovascular DiseasesHereditary Autoinflammatory DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesSkin Diseases, GeneticSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, Vascular

Intervention Hierarchy (Ancestors)

EndoribonucleasesRibonucleasesEsterasesHydrolasesEnzymesEnzymes and CoenzymesEosinophil Granule ProteinsImmunoproteinsBlood ProteinsProteinsAmino Acids, Peptides, and Proteins

Study Officials

  • Hüseyin TE Ozer, Assoc. Prof.

    Cukurova University, Faculty of Medicine, Rheumatology-Immunology Department

    STUDY CHAIR

  • Eren Erken, Prof. Dr.

    Cukurova University, Faculty of Medicine, Rheumatology-Immunology Department

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Didem Arslan Tas

Study Record Dates

First Submitted

April 24, 2012

First Posted

April 25, 2012

Study Start

January 1, 2002

Primary Completion

December 1, 2002

Study Completion

December 1, 2002

Last Updated

April 26, 2012

Record last verified: 2012-04

Locations

TU(1)