Community-acquired Pneumonia in Buskerud County in Norway
Community-acquired Pneumonia: A Prospective Observational Study to Explore Etiology, Risk Factors and Potential Predictors for re- Admittance to Hospital and All-cause Mortality
1 other identifier
observational
270
1 country
1
Brief Summary
The purpose of this study is to determine the etiology of community-acquired pneumonia, to assess risk factors and to investigate potential prognostic biomarkers of serious disease and fatal outcome.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2008
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2012
CompletedFirst Submitted
Initial submission to the registry
March 22, 2012
CompletedFirst Posted
Study publicly available on registry
March 26, 2012
CompletedMarch 26, 2012
March 1, 2012
3 years
March 22, 2012
March 23, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
all cause mortality
one year
Secondary Outcomes (1)
Re-admission to hospital
One month
Study Arms (1)
Adults with CAP admitted to hospital
All adult patients with CAP admitted to Vestre Viken HF-Buskerud Hospital (VVHF-BH), a 400-bed community general hospital, between January 2008 og January 2011 were evaluated for inclusion in the study.
Eligibility Criteria
All adult patients with CAP admittet to Vestre Viken HF-Buskerud Hospital (VVHF-BH) between January 2008 og January 2011, were evaluated for inclusion in the study.
You may qualify if:
- New infiltrate on chest X-ray and
- Fever \> 38,0 by rectal measurement
- at least one of these additional criteria: Cough +/- expectoration, dyspnoea, respiratory chest pain, crackles or reduced respiratory sounds.
- Criteria must be present within 48 hours after admission
You may not qualify if:
- Patients \< 18 years
- Non infectious cause of lung infiltration (tumors, embolism)
- Bronchial obstruction (tumor, bronchiectasia)
- Hospitalised more than 48 hours or discharged within the last 2 weeks
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Vestre Viken Hospital Trustlead
- Vestre Viken HF - Buskerud Hospitalcollaborator
- Oslo University Hospitalcollaborator
- UMass Medical school, Massachusetts - USAcollaborator
Study Sites (1)
Vestre Viken Hospital Trust
Drammen, Buskerud, 3004, Norway
Related Publications (1)
Holter JC, Muller F, Bjorang O, Samdal HH, Marthinsen JB, Jenum PA, Ueland T, Froland SS, Aukrust P, Husebye E, Heggelund L. Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway. BMC Infect Dis. 2015 Feb 15;15:64. doi: 10.1186/s12879-015-0803-5.
PMID: 25887603DERIVED
Biospecimen
whole blood, serum, plasma, blood culture, airways specimens, urine
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Lars Heggelund, MD, PhD
Vestre Viken Hospital Trust and Oslo University Hospital
- STUDY CHAIR
Einar Husebye, MD, PhD
Vestre Viken Hospital Trust
- PRINCIPAL INVESTIGATOR
Jan C Holter, MD
Vestre Viken Hospital Trust
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 22, 2012
First Posted
March 26, 2012
Study Start
January 1, 2008
Primary Completion
January 1, 2011
Study Completion
January 1, 2012
Last Updated
March 26, 2012
Record last verified: 2012-03