Prognostic Features for Mortality in Young Adults With Pneumonia

NCT00845312 | Completed

• 1 other identifier: CTIL
• Study Type: observational
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

Pneumonia is a major cause of mortality and morbidity. A large body of evidence concerning the mortality risk factors in elderly patients with pneumonia has been reported; however, less is known about causes of mortality in patients of sixty and less. We noted a relatively substantial rate of short term mortality in this group of patients that were admitted to our institution. Therefore, we aimed to estimate the mortality rate and to identify risk factors for mortality among patients of sixty years old and less that were admitted with community acquired pneumonia.

Conditions

Pneumonia

Keywords

Age; Mortality

Study Arms (1)

Complicated hospitalization

Patients 60 years old or younger, who were diagnosed with community acquired pneumonia (CAP) between March 1, 2005 and December 31, 2008 were retrospectively analyzed for risk factors for severe morbidity or mortality. was defined as at least one of the following parameters: hospitalization longer than ten days, admission to intensive care unit and in- hospital mortality. Otherwise, the hospitalization was defined uncomplicated .The Rambam hospital Institutional Review Board approved the study.

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients that were admitted with community acquired pneumonia to Rambam Medical Center between the dates January 1, 2004 until December 31, 2008

You may qualify if:

• Patients with the diagnosis of community acquired pneumonia Age between 18-60

You may not qualify if:

• Age less than 18 and more than 60 Transfer from another hospital Hospitalization for any cause other than CAP during the 30 days prior to admission Hospital acquired pneumonia Partial antibiotic treatment before admission.

Sponsors & Collaborators

• Rambam Health Care Campus: lead

Study Sites (1)

Rambam Medical Center

Haifa, 31096, Israel

Location

Related Publications (1)

• Braun E, Domany E, Kenig Y, Mazor Y, Makhoul BF, Azzam ZS. Elevated red cell distribution width predicts poor outcome in young patients with community acquired pneumonia. Crit Care. 2011 Aug 11;15(4):R194. doi: 10.1186/cc10355.

  PMID: 21835005 DERIVED

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Zaher S Azzam, MD

  Head Of Internal Medicine "B"

  STUDY CHAIR

• Eyal Braun, MD

  Deputy Head of Internal Medicine "B"

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 15, 2009
• First Posted: February 18, 2009
• Study Start: March 1, 2009
• Primary Completion: December 1, 2009
• Study Completion: May 1, 2010
• Last Updated: February 15, 2011

Record last verified: 2009-02

Locations

IL (1)