NCT01561326

Brief Summary

Objective: Previous studies have suggested that psycho-educational interventions delivered by telephone improve adherence to initial colposcopy after an abnormal Pap smear. To further explore strategies for enhanced follow-up to medical care recommendations, we studied the impact of a theory-guided cognitive-affective barriers counseling intervention, delivered at 2-4 weeks before the colposcopy appointment, for inner city women. The comprehensive telephone barriers intervention was compared to an enhanced comparison group and a group that received tailored print materials. Methods: Participants (N = 211) were recruited through a colposcopy clinic and randomly assigned to: 1) telephone assessment of barriers to follow up adherence recommendations combined with tailored telephone barriers counseling; 2) telephone assessment combined with tailored barriers print brochure; or 3) telephone assessment with no barriers counseling. Participants were assessed at baseline, 1-week, 9 and 15 months post-colposcopy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
211

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2005

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2005

Completed
6.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

March 20, 2012

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 23, 2012

Completed
Last Updated

March 23, 2012

Status Verified

March 1, 2012

Enrollment Period

6.1 years

First QC Date

March 20, 2012

Last Update Submit

March 21, 2012

Conditions

Keywords

cervical cancerfollow-upPap testMedical managementColposcopy

Outcome Measures

Primary Outcomes (1)

  • Adherence to diagnostic colposcopy appointment

    Adherence to initial diagnostic colposcopy will be assessed for each participant through tracking of clinic reports/patient medical records immediately post-colposcopy. Adherence will be measured dichotomously with patients who attend their initial appointment or who cancel their initial colposcopy appointment but reschedule within one month of their original date deemed adherent and eligible for follow-up assessments.

    1-week Post-Colposcopy

Secondary Outcomes (1)

  • Adherence to long-term follow-up medical recommendations

    9- and 15-months post-index appointment

Study Arms (3)

Cognitive-affective barriers counseling delivered by phone

EXPERIMENTAL

Standard care plus cognitive-affective barriers counseling delivered by phone , i.e., culturally-relevant/sensitive barrier-specific messages drawn from a pre-developed library designed to counsel individuals regarding their specific barriers to adherence

Behavioral: Cognitive-affective barriers counseling

cognitive-affective barriers counseling via brochure

EXPERIMENTAL

Standard care plus cognitive-affective barriers counseling delivered via mail-home print material

Behavioral: Cognitive-affective barriers counseling via brochure

standard care

ACTIVE COMPARATOR

Cognitive-affective barriers (CAB) assessment delivered via phone; receipt of a notification letter from physician regarding abnormal Pap test result, need to undergo colposcopy, appointment date and clinic contact numbers; telephone confirmation and post-card appointment reminder

Behavioral: standard care

Interventions

Culturally-relevant/sensitive barrier-specific messages drawn from a pre-developed library designed to counsel individuals regarding their specific barriers to adherence, e.g., by increasing risk-related knowledge, providing accurate outcome and self-efficacy expectancies, addressing health-related values and goals, moderating risk-related affect, or offering active plans and strategies to assist with self-regulation

Cognitive-affective barriers counseling delivered by phone

Culturally-relevant/sensitive barrier-specific messages drawn from a pre-developed library designed to counsel individuals regarding their specific barriers to adherence via brochure, e.g., by increasing risk-related knowledge, providing accurate outcome and self-efficacy expectancies, addressing health-related values and goals, moderating risk-related affect, or offering active plans and strategies to assist with self-regulation

cognitive-affective barriers counseling via brochure
standard careBEHAVIORAL

Cognitive-affective barriers (CAB) assessment delivered via phone; receipt of a notification letter from physician regarding abnormal Pap test result, need to undergo colposcopy, appointment date and clinic contact numbers; telephone confirmation and post-card appointment reminder

standard care

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • women 18 years old or older
  • have recently received an abnormal Pap smear indicative of oncogenic HPV
  • have been referred for initial colposcopic evaluation at the Women's Care Center at Temple University Hospital
  • able to communicate with ease in English

You may not qualify if:

  • unable to communicate readily in English
  • do not have access to a telephone
  • have a history of any malignancy
  • display current evidence of positive invasive carcinoma of the cervix
  • display presence of another life-threatening medical condition
  • show evidence of dementia
  • prior participation in research study
  • HIV

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States

Location

MeSH Terms

Conditions

Uterine Cervical Neoplasms

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Uterine NeoplasmsGenital Neoplasms, FemaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsUterine Cervical DiseasesUterine DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Officials

  • Suzanne M. Miller-Halegoua, Ph.D.

    Fox Chase Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2012

First Posted

March 23, 2012

Study Start

May 1, 2005

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

March 23, 2012

Record last verified: 2012-03

Locations