Economic Evaluation of Three Populational Screening Strategies for Cervical Cancer
CRICERVA
1 other identifier
interventional
20,994
1 country
1
Brief Summary
The aim of this study was to compare the effectiveness and the costs of three types of population interventions to increase the number of female participants in the screening programmes for cancer of the cervix carried out by Primary Care in four Basic Health Care Areas.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Sep 2010
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2010
CompletedFirst Submitted
Initial submission to the registry
June 10, 2011
CompletedFirst Posted
Study publicly available on registry
June 15, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedJune 15, 2011
June 1, 2011
2.3 years
June 10, 2011
June 14, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Clinical effectiveness measures
The main effectiveness measures of this evaluation would be the total number of cytologies performed, HPV infections detected, lesions of different grades detected, episodes of cancer detected and the number of deaths avoided
Third year
Costs measures
Include costs of diagnosis, interventions and treatment for all women * Diagnosis: cost of cytology, HPV determination test and control visit by the midwife or gynaecologist * Interventions: cost of a full-time administrator, personalized screening invitation letters, informative leaflets and phone calls * Treatment: will depend on the state of health of the women but may include the costs of the visits to the gynaecologist, cytology tests, HPV determination, control visits with the physician, costs of radical hysterectomy, radiotherapy, chemotherapy, etc
Third year
Study Arms (3)
invitation letter
EXPERIMENTALto participate in the screening
Invitation letter, informative leaflet and phone call reminder
EXPERIMENTALto participate in the screening
Invitation letter and informative leaflet
EXPERIMENTALto participate in the screening
Interventions
Cost-effectiveness analysis of 3 strategies to increase the recruitment of population screening for cervical cancer. These interventions will be compared to the current opportunistic screening strategy
Eligibility Criteria
You may qualify if:
- ,994 women from 30 to 70 years of age with incorrect screening criteria (data obtained from Electronic Medical Records) ascribed to the Basic Health Care Area will be included in the study. Incorrect screening will be defined as \[9\]:
- \- No cytology in the last 3 years from women between 30 to 40 years,
- \- No cytology in the previous 5 years from women between 40 to 65 years,
- \- No previous cytology history for females older than 65 years or women who have not had their last cytology before the age of 60
You may not qualify if:
- hysterectomised women, with a current history of pre-malignant lesions (Atypical glandular cells of undetermined significance, Atypical squamous cells of undetermined significance, Low grade Squamous Intraepithelial Lesion, High grade Squamous Intraepithelial Lesion), carcinoma in situ and cervical-uterine cancer, HIV positive or other causes of immunosuppression (since these women follow a specific protocol);
- those residing outside the study setting for more than 6 months;
- those ascribed to the study Basic Health Care Area but with a physician assigned in an UBA (General Practicioner and Nurse Team) of another zone different from the one considered in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
IDIAP Jordi Gol
Barcelona, Barcelona, Spain
Related Publications (4)
Trapero-Bertran M, Acera Perez A, de Sanjose S, Manresa Dominguez JM, Rodriguez Capriles D, Rodriguez Martinez A, Bonet Simo JM, Sanchez Sanchez N, Hidalgo Valls P, Diaz Sanchis M. Cost-effectiveness of strategies to increase screening coverage for cervical cancer in Spain: the CRIVERVA study. BMC Public Health. 2017 Feb 14;17(1):194. doi: 10.1186/s12889-017-4115-0.
PMID: 28196467DERIVEDAcera A, Manresa JM, Rodriguez D, Rodriguez A, Bonet JM, Trapero-Bertran M, Hidalgo P, Sanchez N, de Sanjose S. Increasing Cervical Cancer Screening Coverage: A Randomised, Community-Based Clinical Trial. PLoS One. 2017 Jan 24;12(1):e0170371. doi: 10.1371/journal.pone.0170371. eCollection 2017.
PMID: 28118410DERIVEDAcera A, Manresa JM, Rodriguez D, Rodriguez A, Bonet JM, Sanchez N, Hidalgo P, Soteras P, Toran P, Trapero-Bertran M, Lozano I, De Sanjose S. Analysis of three strategies to increase screening coverage for cervical cancer in the general population of women aged 60 to 70 years: the CRICERVA study. BMC Womens Health. 2014 Jul 16;14:86. doi: 10.1186/1472-6874-14-86.
PMID: 25026889DERIVEDAcera A, Rodriguez A, Trapero-Bertran M, Soteras P, Sanchez N, Bonet JM, Manresa JM, Hidalgo P, Toran P, Prieto G. Economic evaluation of three populational screening strategies for cervical cancer in the county of Valles Occidental: CRICERVA clinical trial. BMC Health Serv Res. 2011 Oct 19;11:278. doi: 10.1186/1472-6963-11-278.
PMID: 22011387DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Amelia Acera, Doctor
Institut CatalĂ de la Salut (ICS)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 10, 2011
First Posted
June 15, 2011
Study Start
September 1, 2010
Primary Completion
December 1, 2012
Study Completion
December 1, 2013
Last Updated
June 15, 2011
Record last verified: 2011-06