Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise

NCT01555775 | Completed

• 1 other identifier: SFRH/BD/75276/2010
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after resistance exercise, in muscle damage, oxidative stress, inflammation and functional recovery. It is hypothesised if the ingestion of a milk shake with skimmed milk and fruit (strawberry and banana) has the same impact on markers of muscle damage, oxidative stress, inflammation and functional recovery induced by resistance exercise, as the intake of a commercial powder with the same CHO and protein amounts. Fifteen adult athletes from the Portuguese Athletic Federation will complete 2 trials separated at least by 2 weeks. Alternate legs and drinks will be used in each trial and participants will be overnight-fasted. This study will have a single-blind, randomized, crossover, repeated-measures experimental design. In each trial, after warm-up, the eccentric peak torque of the knee joint extensors will be determined using an isokinetic dynamometer. After this, participants will complete an isokinetic exercise until exhaustion at a constant angular velocity of 60° • s-1. After the exhaustion protocol, athletes will perform again the peak torque determination. Immediately after, participants will drink the P-CHO supplement or MS during the first 2 h. Both drinks will contain 0.8-1.2 g carbohydrates • kg-1 • h-1 and 0.2-0.4 g protein • kg-1 • h-1. Twenty four and 48 h after the exhaustion protocol participants will return to the laboratory to repeat the peak torque determination. Blood samples will be collected before warming-up, immediately and 2 h after the last peak torque determination and 24 h and 48 h after. Serum samples will be analyzed for creatine kinase, lactate dehydrogenase, interleukine-6, protein carbonyls and total antioxidant status. The delayed onset muscle soreness, using a visual analogue scale, and girths will be measured at the same moments as blood sampling. Two-way repeated-measures ANOVA will be used for statistical analysis of the data.

Conditions

Muscle Damage; Inflammation; Oxidative Stress; Functional Recovery

Keywords

exercise-induced muscle damage; nutritional recovery; nutritional supplement; natural food

Outcome Measures

Primary Outcomes (8)

• Maximal peak torque of the knee extensors muscles

  To monitor functional recovery

  Up to 48 h

• Creatine kinase

  To monitor muscle damage

  Up to 48 h

• Lactate dehydrogenase

  To monitor muscle damage

  Up to 48 h

• Interleukine-6

  To monitor the inflammatory process

  Up to 48 h

• Total antioxidant status

  To monitor oxidative stress

  Up to 48 h

• Delayed onset muscle soreness

  By a visual analogue scale, 10 cm in length. To monitor muscle soreness

  Up to 48 h

• Mid-thigh girth, Three other girths will be measured: 5, 15 and 25 cm above the superior border of the patella.

  To monitor the inflammatory process

  Up to 48 h

• Protein carbonyls

  To monitor oxidative stress

  Up to 48 h

Secondary Outcomes (3)

• Percentage of body fat

  1 week before the first trial

• Food records

  2 days before each trial

• Physical activity records

  2 days before each trial

Study Arms (2)

P-CHO supplement

EXPERIMENTAL

This group will drink the P-CHO supplement in the first trial and the fruit milk shake in the second.

Dietary Supplement: P-CHO supplement

Fruit Milk Sake

EXPERIMENTAL

This group will drink the fruit milk shake in the first trial and the P-CHO supplement in the second.

Dietary Supplement: Fruit Milk Shake

Interventions

P-CHO supplement DIETARY_SUPPLEMENT

In the first trial, this group will drink a protein (P)-carbohydrate (CHO) supplement and in the second trial the fruit milk shake.

Also known as: Available in a common local market.

P-CHO supplement

Fruit Milk Shake DIETARY_SUPPLEMENT

The fruit content of the milk shake will be 100 g of strawberry and the amount of banana necessary to guaranty 0.8-1.2 g CHO • kg-1 BW • h-1.

Also known as: Strawberry, bananas, skimmed milk

Fruit Milk Sake

Eligibility Criteria

• Age: 18 Years+
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• healthy and lactose tolerant

Sponsors & Collaborators

• Universidade do Porto: lead

Study Sites (1)

Faculdade de Desporto, Universidade do Porto

Porto, 4200-450, Portugal

Location

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Related Links

• Web page of the institution that funds the individual Ph.D. grant (SFRH/BD/75276/2010)

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• José Soares, PhD

  Faculdade de Desporto, Universidade do Porto

  STUDY DIRECTOR

• Monica V. Sousa, BSc

  Faculdade de Desporto, Universidade do Porto

  PRINCIPAL INVESTIGATOR

• Vitor H Teixeira, PhD

  Faculdade de Ciências da Nutrição e Alimentação, Universidade do Porto

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: BSc

Study Record Dates

• First Submitted: March 7, 2012
• First Posted: March 15, 2012
• Study Start: March 1, 2012
• Primary Completion: March 1, 2012
• Study Completion: May 1, 2012
• Last Updated: January 16, 2013

Record last verified: 2013-01

Locations

PT (1)