Use of Alternative Medicine in Patients With Dementia and Mild Cognitive Dysfunction

NCT01554475 | Completed

• 1 other identifier: 2011/1705(REK)
• Study Type: observational
• Target: 151
• Locations: 1 country
• Sites: 1

Brief Summary

So far, no drugs have shown to stop or delay the pathological processes of dementia. Available pharmacological treatment includes a small number of drugs; cholinesterase inhibitors like donepezil, galantamine and rivastigmine, and the NMDA receptor antagonist memantine, all of which only affect the symptoms of the disease. At the same time, alternative medicines like herbal products and dietary supplements are often intensively marketed with the assertion of curative or alleviating effects on dementia. The documentation of clinical effects, side effects and the potential for interaction with prescribed drugs are, however, generally scarce. The aims of this study are to make a survey of the use of alternative medicine in patients with dementia and mild cognitive dysfunction attending the investigators out-patient dementia clinic, and to assess the interaction potential with the patient's other medications.

Conditions

Dementia; Cognitive Impairment

Keywords

herbal drugs; dietary supplements; drug interactions

Outcome Measures

Primary Outcomes (1)

• Number of patients taking alternative medicines

  The patient's use of alternative medicine(s) on a given point of time (the consultation date) as reported by the patient or by the next of kin who is the patient's companion during the consultation. The results will be presented as the number of patients taking alternative medicines

  Up to 2 years

Secondary Outcomes (2)

• Numbers of potential and clinical relevant interactions

  Up to 2 years

• The patient's subjective experiences with alternative medicines

  up to 2 years

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients diagnosed with dementia, under follow-up at Kløveråsen out-patient clinic

You may qualify if:

• diagnosed with dementia

Sponsors & Collaborators

• University Hospital of North Norway: lead
• Kløveråsen Center for dementia, Bodø: collaborator

Study Sites (1)

Kløveråsen

Bodø, N-8076, Norway

Location

MeSH Terms

Conditions

Dementia; Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Cognition Disorders

Study Officials

• Trude Giverhaug, PhD

  University Hospital North-Norway

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 13, 2012
• First Posted: March 15, 2012
• Study Start: March 1, 2012
• Primary Completion: October 1, 2014
• Study Completion: October 1, 2014
• Last Updated: February 18, 2015

Record last verified: 2015-02

Locations

NO (1)