NCT01553604

Brief Summary

This study was designed to determine whether the duration of dressing wear following augmentation mammaplasty influence skin colonization and eventually surgical site infections rates.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 12, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 14, 2012

Completed
1.3 years until next milestone

Study Start

First participant enrolled

July 1, 2013

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2015

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

September 6, 2019

Status Verified

September 1, 2019

Enrollment Period

1.5 years

First QC Date

March 12, 2012

Last Update Submit

September 3, 2019

Conditions

Keywords

breast prosthesis implantationbandagesskin colonizationsurgical site infectionaugmentation mammaplastydressing wear time

Outcome Measures

Primary Outcomes (1)

  • skin colonization

    skin colonization will be measured through semi-quantitative cultures of samples collected pre-dressing and on 6th postoperative day.

    6 days postoperatively

Secondary Outcomes (1)

  • surgical site infection

    30 days postoperatively

Study Arms (2)

Postoperative day 6

EXPERIMENTAL

Dressing is removed on the sixth postoperative day

Procedure: augmentation mammaplasty

Postoperative day 1

EXPERIMENTAL

Dressing is removed on the first postoperative day

Procedure: augmentation mammaplasty

Interventions

Dressing is removed on the first postoperative day

Postoperative day 1

Eligibility Criteria

Age18 Months - 60 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • candidate to breast prosthesis implantation
  • body mass index under 30Kg/m2

You may not qualify if:

  • pregnancy, delivery or breast feeding during the last 12 months
  • body mass index over 30Kg/m2
  • breast cancer history
  • previous breast surgery
  • hard smoking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital das Clínicas Samuel Libanio

Pouso Alegre, Minas Gerais, 37550000, Brazil

Location

Related Publications (2)

  • Mendes Dde A, Veiga DF, Veiga-Filho J, Fonseca FE, de Paiva LF, Novo NF, Loyola AB, Ferreira LM. Application time for postoperative wound dressing following breast augmentation with implants: study protocol for a randomized controlled trial. Trials. 2015 Jan 27;16:19. doi: 10.1186/s13063-014-0529-5.

    PMID: 25623237BACKGROUND
  • Mendes DA, Veiga DF, Veiga-Filho J, Loyola ABAT, Paiva LF, Novo NF, Sabino-Neto M, Ferreira LM. Influence of dressing application time after breast augmentation on cutaneous colonization: A randomized clinical trial. J Plast Reconstr Aesthet Surg. 2018 Jun;71(6):906-912. doi: 10.1016/j.bjps.2018.01.021. Epub 2018 Feb 21.

MeSH Terms

Conditions

Surgical Wound Infection

Condition Hierarchy (Ancestors)

Wound InfectionInfectionsPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Daniela F Veiga, MD, PhD

    Universidade Federal de São Paulo

    STUDY DIRECTOR
  • Joel Veiga-Filho, MD, PhD

    Universidade do Vale do Sapucaí

    PRINCIPAL INVESTIGATOR
  • Lydia M Ferreira, MD, PhD

    Universidade Federal de São Paulo

    STUDY CHAIR
  • Denise A Mendes, MD, PhD

    Universidade Federal de São Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 12, 2012

First Posted

March 14, 2012

Study Start

July 1, 2013

Primary Completion

January 1, 2015

Study Completion

September 1, 2015

Last Updated

September 6, 2019

Record last verified: 2019-09

Locations