NCT01532258

Brief Summary

This research is examining whether an 8-week online nutritional programming based on a Mediterranean diet can achieve meaningful increase intake of a Mediterranean based diet and improvements in measures of body weight and laboratory measures of oxidative stress, a risk marker for cardiovascular disease. This study will also examine whether weekly short support and communication from a medical assistant (MA) in a primary care setting in addition to the online program will result in better program adherence and have a positive impact on health.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2012

Shorter than P25 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 23, 2011

Completed
5 months until next milestone

First Posted

Study publicly available on registry

February 14, 2012

Completed
2 months until next milestone

Study Start

First participant enrolled

April 1, 2012

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2012

Completed
Last Updated

May 11, 2022

Status Verified

May 1, 2022

Enrollment Period

4 months

First QC Date

September 23, 2011

Last Update Submit

May 6, 2022

Conditions

Keywords

BMIWeight lossNutritionDietMediterranean dietOnline programweb-based programOxidative stressF2 isoprostanes

Outcome Measures

Primary Outcomes (2)

  • Weight Loss

    To see if the 8-week Mediterranean diet online program (GFFY) can lead to weight loss at 12 week.

    12 weeks

  • Effect of Weekly Communications on Adherence and Program Efficacy

    To see if extension of the patient/medical provider relationship through weekly emails by a medical assistant who addresses the program behavioral goals set by the patient leads to greater weight loss.

    12 weeks

Secondary Outcomes (6)

  • Effect on Oxidative Stress

    12 weeks

  • Correlation between MA Support and Program Utilization

    12 weeks

  • Effect on Physical and Mental Health

    12 weeks

  • Sustainability of Weight Loss

    24 weeks

  • Dietary Improvements

    12 weeks

  • +1 more secondary outcomes

Study Arms (3)

Control Group

NO INTERVENTION

No intervention provided. These participants will receive access to the Go! Foods for You program after the research trial has been completed (12 weeks after registration).

GFFY-1 without weekly MA support

ACTIVE COMPARATOR

Utilization of the 8-week online nutrition program Go! Foods for You without weekly contact from staff at the medical provider's office.

Behavioral: Go! Foods for You without Weekly MA Support.

GFFY-2 with weekly MA support

ACTIVE COMPARATOR

Utilization of the 8-week online nutrition program combined with weekly contact from the staff at the medical provider's office.

Behavioral: Go! Foods for You with Weekly MA Support.

Interventions

* Participants access and utilize an 8-week online program which provides educational materials and weekly activities based on a Mediterranean diet and dietary "practices" that have been associated with healthy weights. * Each day participants receive educational materials related to the nutritional science of a Mediterranean diet. Each week (1) a new theme for the daily educational materials is presented and (2) participants are asked to schedule "activities" on a built in calendar and practice the activity throughout the week.

GFFY-1 without weekly MA support

* Participants access and utilize an 8-week online program which provides educational materials and weekly activities based on a Mediterranean diet and dietary "practices" that have been associated with healthy weights. * In addition to the 8-week online program, participants receive weekly support by Medical Assistants (MA) over the phone or by email to establish a relationship and maintain program adherence by discussing the previous week's behavioral goals and setting weekly behavioral goals.

GFFY-2 with weekly MA support

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body Mass Index (BMI) of 25 or greater.
  • Age 18 to 70 years old.
  • Patient of a participating Internal Medicine or Family Medicine primary care provider at a Cleveland Clinic Family Health Center.
  • Registered on the Cleveland Clinic's electric medical records, My Chart.

You may not qualify if:

  • Women who are pregnant or planning to be pregnant in the next 6 months.
  • No easy internet and email access at place of residence.
  • No access to a scale at place of residence for weekly weight measurement.
  • Sudden unintentional weight loss or weight gain in the past 3 months due to medical illness
  • Currently involved in a weight loss program
  • unwilling to be in the wait-list control group where participant will not have access to the program for 3 months
  • unwilling to log onto the internet on a regular basis for the duration of the study (3-4 months)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States

Location

MeSH Terms

Conditions

ObesityWeight Loss

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBody Weight Changes
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Coordinator

Study Record Dates

First Submitted

September 23, 2011

First Posted

February 14, 2012

Study Start

April 1, 2012

Primary Completion

August 1, 2012

Study Completion

August 1, 2012

Last Updated

May 11, 2022

Record last verified: 2022-05

Locations