Study Stopped
The restrictions on research imposed for the COVID-19 pandemic prevented us from continuing recruitment and visits. At this stage our funding is not sufficient to continue enrollment so we will put the study in a hold pattern.
Characterization of Adult Subjects for Asthmatic Research Studies
CASA
1 other identifier
observational
259
1 country
1
Brief Summary
This study is designed to characterize subjects in terms of the nature and severity of their asthma and in terms of conditions that may alter the clinical expression of asthma. Some features will be obtained in all subjects. These include a medical history and baseline lung function tests. This characterization forms the basis for our database that facilitates research protocols.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2010
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2010
CompletedFirst Submitted
Initial submission to the registry
January 6, 2012
CompletedFirst Posted
Study publicly available on registry
January 11, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2026
September 5, 2025
September 1, 2025
16.2 years
January 6, 2012
September 3, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Airway inflammation
We will measure various indicators of airway inflammation and compare them with various phenotypic characteristics.
Cross-sectional
Study Arms (2)
Asthmatics
Otherwise healthy asthmatic subjects
Healthy controls
Healthy individuals without evidence of pulmonary disease.
Eligibility Criteria
Asthmatics and healthy control
You may qualify if:
- Age 18 years and older
You may not qualify if:
- History of lung disease other than asthma
- An upper respiratory tract infection or an exacerbation of their asthma within the preceding 4-6 weeks.
- Persons who have smoked \> 5 cigarettes per month and have a total pack-year smoking history \> 10 packs.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of California, San Francisco
San Francisco, California, 94143, United States
Related Links
Biospecimen
Samples of induced sputum and blood for DNA and RNA extraction, plasma, and serum will be banked in the UCSF Airway Tissue Bank.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
John Fahy, MD
University of California, San Francisco
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 6, 2012
First Posted
January 11, 2012
Study Start
May 1, 2010
Primary Completion (Estimated)
July 1, 2026
Study Completion (Estimated)
July 1, 2026
Last Updated
September 5, 2025
Record last verified: 2025-09