NCT00594750

Brief Summary

The purpose of this study is to identify the causes of asthma that were not previously suspected, to better understand the effects of inhaled steroids on asthma and to identify new way to treat asthma.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2006

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 2, 2008

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 16, 2008

Completed
11.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2019

Completed
5.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 5, 2025

Completed
Last Updated

March 9, 2026

Status Verified

March 1, 2026

Enrollment Period

13.5 years

First QC Date

January 2, 2008

Last Update Submit

March 5, 2026

Conditions

Asthma

Outcome Measures

Primary Outcomes (1)

  • rheological measurements (viscosity and elasticity) in sputum from patients with acute severe asthma

    1-2 years

Study Arms (1)

Asthma

People who have been diagnosed with Asthma

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

emergency deparment, admitted patients in the ICU and inpatient wards

You may qualify if:

  • Male and female subjects with a history of asthma between the ages of 18 to 75 years.
  • Physician diagnosis of asthma.
  • Currently experiencing an acute exacerbation of asthma. This exacerbation may be severe necessitating treatment in the emergency room, ICU, or hospital ward.
  • Ability to provide informed consent.

You may not qualify if:

  • Lung disease other than asthma.
  • Females who are lactating or who are pregnant.
  • Use of recreational drugs in the 1 month preceding the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCSF Airway Clinical Research Center

San Francisco, California, 94143, United States

Location

Related Links

Biospecimen

Retention: SAMPLES WITHOUT DNA

Sputum, whole blood

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • John V Fahy, M.D., M.Sc.

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 2, 2008

First Posted

January 16, 2008

Study Start

May 1, 2006

Primary Completion

November 1, 2019

Study Completion

August 5, 2025

Last Updated

March 9, 2026

Record last verified: 2026-03

Locations

US(1)