NCT01495299

Brief Summary

The purpose of this study is to determine the relationship between intraocular pressure (IOP) fluctuations of glaucoma patients as recorded with an IOP-sensing contact lens (SENSIMED Triggerfish®), during two 24-hour periods, before and after cataract surgery. This device has previously been investigated and shown to be safe and well tolerated.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2011

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

December 12, 2011

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 20, 2011

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
Last Updated

August 21, 2019

Status Verified

August 1, 2019

Enrollment Period

10 months

First QC Date

December 12, 2011

Last Update Submit

August 19, 2019

Conditions

Keywords

relationshipIOP fluctuationsglaucomacataract surgerySENSIMED Triggerfish

Outcome Measures

Primary Outcomes (1)

  • 24-h IOP patterns

    24 hour

Study Arms (1)

cataract patients with glaucoma

Device: Phacoemulsification with implantation of intraocular lens (CE-IOL) SENSIMED Triggerfish

Interventions

Phacoemulsification (standard cataract extraction surgery)

cataract patients with glaucoma

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

glaucoma patients scheduled to undergo cataract surgery.

You may qualify if:

  • Subject is able to comply with the study procedures
  • years old
  • Subjects diagnosed with glaucoma, based on presence of repeatable visual field loss and/or glaucomatous optic neuropathy based on masked review of optic disc stereophotographs and under ocular hypotensive treatment, or diagnosed with ocular hypertension, with an IOP of \> 22 mmHg at the screening visit and under ocular hypotensive treatment.
  • Subject has consented to be in the trial
  • Visual acuity of 20/200 or better
  • Presence of cataract requiring phacoemulsification with lens exchange
  • Ability to understand the character and individual consequences of the study
  • For women of childbearing potential, adequate contraception

You may not qualify if:

  • Subjects presenting with any of the following criteria will not be included in the trial:
  • Subjects with contraindications for wearing contact lenses
  • Severe dry eye syndrome
  • Keratoconus or other corneal abnormality
  • Conjunctival or intraocular inflammation
  • Eye surgery prior to and throughout the study.
  • Full frame metal glasses during SENSIMED Triggerfish® monitoring
  • Known hypersensitivity to silicone, plaster or ocular anesthesia (proparacaine)
  • Pregnancy and lactation
  • Simultaneous participation in other clinical studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCSD

La Jolla, California, United States

Location

MeSH Terms

Conditions

Glaucoma

Interventions

PhacoemulsificationLens Implantation, Intraocular

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases

Intervention Hierarchy (Ancestors)

Cataract ExtractionRefractive Surgical ProceduresOphthalmologic Surgical ProceduresSurgical Procedures, OperativeUltrasonic Surgical Procedures
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 12, 2011

First Posted

December 20, 2011

Study Start

December 1, 2011

Primary Completion

October 1, 2012

Study Completion

October 1, 2012

Last Updated

August 21, 2019

Record last verified: 2019-08

Locations