NCT01495312

Brief Summary

The purpose of this study is to determine the relationship between Intraocular Pressure (IOP) fluctuations of glaucoma patients as recorded with an IOP-sensing contact lens (SENSIMED Triggerfish®), during two 24-hour periods after selective laser trabeculoplasty (SLT) for routine treatment of glaucoma.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 2011

Geographic Reach
1 country

2 active sites

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2011

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

December 12, 2011

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 20, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 12, 2013

Completed
Last Updated

May 30, 2019

Status Verified

May 1, 2019

Enrollment Period

8 months

First QC Date

December 12, 2011

Last Update Submit

May 28, 2019

Conditions

Keywords

IOP fluctuationsduring two 24-hour periods

Outcome Measures

Primary Outcomes (1)

  • IOP

    2 months after SLT

Study Arms (1)

SLT

EXPERIMENTAL
Device: SLT (selective laser trabeculoplasty ) SENSIMED Triggerfish

Interventions

SLT (single session; 180 to 360 degrees of angle will be treated)

SLT

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is able to comply with the study procedures
  • years old
  • Subjects diagnosed with glaucoma, based on presence of repeatable visual field loss and/or glaucomatous optic neuropathy based on masked review of optic disc stereophotographs and under ocular hypotensive treatment, or diagnosed with ocular hypertension, with an IOP of \> 22 mmHg at the screening visit and under ocular hypotensive treatment.
  • Subject has consented to be in the trial
  • Visual acuity of 20/200 or better
  • Ability to understand the character and individual consequences of the study
  • For women of childbearing potential, adequate contraception

You may not qualify if:

  • Subjects presenting with any of the following criteria will not be included in the trial:
  • Subjects with contraindications for wearing contact lenses
  • Severe dry eye syndrome
  • Keratoconus or other corneal abnormality
  • Conjunctival or intraocular inflammation
  • Eye surgery prior to and throughout the study.
  • Full frame metal glasses during SENSIMED Triggerfish® monitoring
  • Known hypersensitivity to silicone, plaster or ocular anesthesia (proparacaine)
  • Pregnancy and lactation
  • Simultaneous participation in other clinical studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

UCSD

La Jolla, California, 92037, United States

Location

UCSD

La Jolla, California, United States

Location

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular HypertensionEye Diseases
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Associate

Study Record Dates

First Submitted

December 12, 2011

First Posted

December 20, 2011

Study Start

December 1, 2011

Primary Completion

August 1, 2012

Study Completion

August 12, 2013

Last Updated

May 30, 2019

Record last verified: 2019-05

Locations