NCT01476995

Brief Summary

The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known diagnoses identified by medical doctors. Specifically, the investigators hypothesize that the organ system involving any of a series of known active diagnoses will be identified in the EPIC ClearView Response Scale report with the intention of providing potential triage capabilities.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
353

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2010

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2010

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

October 3, 2011

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 22, 2011

Completed
Last Updated

November 22, 2011

Status Verified

November 1, 2011

Enrollment Period

9 months

First QC Date

October 3, 2011

Last Update Submit

November 18, 2011

Conditions

Keywords

Cardiovascular systemgastrointestinal systemkidneysliverlungs

Outcome Measures

Primary Outcomes (1)

  • Agreement of ClearView Scan versus Active Diagnosis

    Statistical agreement will be assessed between the 0-25 ClearView Response Scale and the physician's diagnoses recorded within the medical record, on a per-subject basis.

    At time of ClearView Scan (Single study visit only, with no follow-up. The study endpoint will be reported for day 0, the day of the study visit).

Secondary Outcomes (1)

  • Sensitivity and Specificity of ClearView Scan versus Active Diagnosis

    Single study visit only, with no follow-up. The study endpoint will be reported for day 0, the day of the study visit.

Study Arms (2)

Controls

Men and women ages 18-85 lacking any medical diagnosis (as defined in the protocol) of one or more of the following systems/organs: cardiovascular system; gastrointestinal system; kidneys; liver; lungs.

Five Diagnosis Group

Men and women ages 18-85 with at least one active medical diagnosis (as defined in the protocol) of one or more of the following systems/organs: cardiovascular system; gastrointestinal system; kidneys; liver; lungs.

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Men and women ages 18-85 who are inpatients, outpatients, friends/family/staff (controls only) of Greater Baltimore Medical Center in Baltimore, Maryland. Participants cannot have an implantable electrical device (such as a pacemaker) on their body, cannot be pregnant, and cannot be undergoing cancer therapy of any kind.

You may qualify if:

  • Five Diagnosis Group:
  • Sex: Male or Female
  • Age range: 18 to 85
  • Qualifying medical diagnoses (5 diagnosis groups)
  • \- For potential subjects presenting with one of the five qualifying diagnoses, the patient presents with confirmed active medical diagnoses affecting the following systems or organs:
  • Cardiovascular system: coronary artery disease, left sided congestive heart failure with EF \<50%, valvular heart disease, atrial fibrillation, and hypertension
  • Kidney: pyelonephritis, acute renal failure, or chronic renal failure stages II-V
  • Liver: viral hepatitis, alcoholic hepatitis, steatohepatitis, or cirrhosis
  • Pulmonary system: asthma, COPD, bronchitis, emphysema, or pneumonia
  • Gastrointestinal/Endocrine: inflammatory bowel disease (including Crohn's disease, ulcerative colitis, or diverticulitis), peptic ulcer disease, IBS, cholecystitis, pancreatitis, or malabsorption disorders (including Celiac Sprue); diabetes (Type 1 and Type 2)
  • The patient or legal representative is able to understand and provide signed consent for the procedure.
  • Every effort will be given to balance subjects by gender, age, and race. At least 60 subjects from each of the 5 diagnostic groups and the 1 control group will be recruited.
  • Control Group:
  • Sex: Male or Female
  • Age range: 18 to 85
  • +9 more criteria

You may not qualify if:

  • Patients \< 18 years in age or \> 85 years in age.
  • Inability or unwillingness to provide informed consent.
  • Patients with pacemakers or another electrical device implanted somewhere in their body.
  • Pregnant women.
  • Patients currently undergoing therapy for cancer of any kind.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Greater Baltimore Medical Cente

Baltimore, Maryland, 21204, United States

Location

Related Links

MeSH Terms

Conditions

Coronary Artery DiseaseHeart FailureHeart Valve DiseasesAtrial FibrillationHypertensionPyelonephritisAcute Kidney InjuryRenal InsufficiencyHepatitis, AlcoholicFatty LiverFibrosisAsthmaPulmonary Disease, Chronic ObstructiveBronchitisEmphysemaPneumoniaInflammatory Bowel DiseasesCrohn DiseaseColitis, UlcerativeDiverticulitisPeptic UlcerIrritable Bowel SyndromeCholecystitisPancreatitisCeliac DiseaseDiabetes Mellitus

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular DiseasesArrhythmias, CardiacPathologic ProcessesPathological Conditions, Signs and SymptomsNephritis, InterstitialNephritisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesPyelitisMale Urogenital DiseasesHepatitisLiver DiseasesDigestive System DiseasesLiver Diseases, AlcoholicAlcohol-Induced DisordersAlcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesChronic DiseaseDisease AttributesRespiratory Tract InfectionsInfectionsGastroenteritisGastrointestinal DiseasesIntestinal DiseasesColitisColonic DiseasesDiverticular DiseasesDuodenal DiseasesStomach DiseasesColonic Diseases, FunctionalGallbladder DiseasesBiliary Tract DiseasesPancreatic DiseasesMalabsorption SyndromesMetabolic DiseasesNutritional and Metabolic DiseasesGlucose Metabolism DisordersEndocrine System Diseases

Study Officials

  • Clair A Francomano, MD

    Greater Baltimore Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2011

First Posted

November 22, 2011

Study Start

September 1, 2010

Primary Completion

June 1, 2011

Study Completion

June 1, 2011

Last Updated

November 22, 2011

Record last verified: 2011-11

Locations