Key Insights

Highlights

Success Rate

90% trial completion (above average)

Published Results

53 trials with published results (10%)

Research Maturity

269 completed trials (50% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

5.6%

30 terminated out of 536 trials

Success Rate

90.0%

+3.5% vs benchmark

Late-Stage Pipeline

20%

105 trials in Phase 3/4

Results Transparency

20%

53 of 269 completed with results

Key Signals

53 with results90% success30 terminated

Data Visualizations

Phase Distribution

364Total
Not Applicable (169)
Early P 1 (3)
P 1 (28)
P 2 (59)
P 3 (42)
P 4 (63)

Trial Status

Completed269
Unknown85
Recruiting82
Terminated30
Not Yet Recruiting23
Withdrawn18

Trial Success Rate

90.0%

Benchmark: 86.5%

Based on 269 completed trials

Clinical Trials (536)

Showing 20 of 20 trials
NCT04807023CompletedPrimary

Decompensation of Cirrhosis and Iron Metabolism

NCT02983968CompletedPrimary

Use of the French Healthcare Insurance Database

NCT06778317Recruiting

mSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis

NCT03311152Not ApplicableCompleted

Circulating Cell-free DNA-based Epigenetic Biomarker mSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis

NCT05170854CompletedPrimary

The Impact of Liver Cirrhosis on Outcomes in Trauma Patients

NCT07634237Not ApplicableNot Yet RecruitingPrimary

Personalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic Encephalopathy

NCT05260268Not ApplicableActive Not Recruiting

Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant

NCT05832229Phase 2RecruitingPrimary

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

NCT02968810Phase 2Active Not RecruitingPrimary

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

NCT06288828Not ApplicableCompletedPrimary

The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis

NCT04939350CompletedPrimary

Evaluation of the Vaccination Coverage of Cirrhotic Patients Followed in the General Hospitals in France in 2021

NCT07585773Not Yet RecruitingPrimary

Effect of Laparoscopic Splenectomy on Renal Function in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up)

NCT04786743Not ApplicableCompleted

Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT

NCT04836923Not ApplicableCompleted

LIFT Intervention in Liver Transplant Candidates

NCT07280390RecruitingPrimary

Microplastics, Cirrhosis and Portal Hypertension

NCT07588373Not Yet RecruitingPrimary

Effect of Laparoscopic Splenectomy on Lipid Profiles in Cirrhotic Patients With Hypersplenism (2-Year Follow-Up)

NCT07322237Phase 4Recruiting

DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis

NCT05548452Phase 1Recruiting

Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease

NCT05027425Phase 2Terminated

Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant

NCT02016196Phase 3CompletedPrimary

Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS

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