EEG Objectification in Neuropsychiatry

NCT01476228 | Unknown

• 1 other identifier: 0394-11-HMO-CTIL
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective of the study is to evaluate the use of EEG in the management and follow-up of neuropsychiatric disorders. Secondary objectives are therefore better understanding of the pathological activations in neural network during neuropsychiatric disorders, their clinical evolution and response to therapies.

Conditions

Personality Disorder; Depression; Neurodegeneration; Alzheimer's Disease; Epilepsy

Outcome Measures

Primary Outcomes (1)

• percentage of fitting (0-100%) of EEG pattern to a previously identified electrophysiological "key"

  The study will decode an EEG-based "key" (or electrophysiological pattern) for specific effect (such as the use of anti-epileptic agent or a certain condition) by comparing EEG before and after the use of this agent. For each patient the statistical fitting of the recorded EEG to the key will be evaluated by percentage (0-100%), describing fitting of the individual patient's EEG to the identified key.

  1 year

Study Arms (1)

study group

EXPERIMENTAL

EEG recording

Device: EEG recording

Interventions

EEG recording DEVICE

EEG recording

study group

Eligibility Criteria

• Age: 15 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• diagnosis of the investigated neuropsychiatric disease

You may not qualify if:

• Other co-existing neuropsychiatric conditions
• Refusal to participate in the study

Sponsors & Collaborators

• Hadassah Medical Organization: lead

Study Sites (1)

HMO

Jerusalem, 91120, Israel

Location

Related Publications (2)

• Arzy S, Collette S, Wissmeyer M, Lazeyras F, Kaplan PW, Blanke O. Psychogenic amnesia and self-identity: a multimodal functional investigation. Eur J Neurol. 2011 Dec;18(12):1422-5. doi: 10.1111/j.1468-1331.2011.03423.x. Epub 2011 May 7.

  PMID: 21554495 RESULT

• Arzy S, Allali G, Brunet D, Michel CM, Kaplan PW, Seeck M. Antiepileptic drugs modify power of high EEG frequencies and their neural generators. Eur J Neurol. 2010 Oct;17(10):1308-12. doi: 10.1111/j.1468-1331.2010.03018.x.

  PMID: 20402743 RESULT

MeSH Terms

Conditions

Personality Disorders; Depression; Nerve Degeneration; Alzheimer Disease; Epilepsy

Condition Hierarchy (Ancestors)

Mental Disorders; Behavioral Symptoms; Behavior; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders

Study Officials

• shahar arzy, MD PhD

  HMO

  PRINCIPAL INVESTIGATOR

Central Study Contacts

shahar arzy, MD PhD

CONTACT

shahar.arzy@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 22, 2011
• First Posted: November 22, 2011
• Study Start: November 1, 2011
• Primary Completion: November 1, 2013
• Study Completion: December 1, 2015
• Last Updated: November 22, 2011

Record last verified: 2011-08

Locations

IL (1)