Effect of Essential Oils in Aromatherapy on Emotional Relaxation

NCT01443871 | Completed DMC

• 1 other identifier: WP-5102031
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this study is to examine and compare electroencephalography (EEG) changes in human subjects directly after inhalation of essential oils from five Thai aromatherapies. The investigators hypothesize that essential oils from Thai aromatherapies may influence the human EEG involving emotional relaxation particularly alpha wave EEG.

Conditions

Healthy

Keywords

Volunteer

Outcome Measures

Primary Outcomes (1)

• electroencephalography (EEG) changes

  The EEG was assessed for 10 minutes in each period; baseline, during and after inhaled the essential oil

  baseline, 10 minutes

Study Arms (2)

Aromatherapy

EXPERIMENTAL

Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the odor for 10 minutes as during inhalation. The last part, the odor was dispersed and assessed EEG activity for 10 minutes as after inhalation.

Other: Aromatherapy

Pure water

PLACEBO COMPARATOR

Experimental procedures were conducted in the morning. Subjects individually entered the closed room where the temperature was kept at 25-26 oC and humidity 50-60%. The subjects were blinded using mask and were seated comfortably with eyes closed during experimental period. The EEG was recorded using silver electrodes. EEG activity was monitored 4 areas (F7, F8, T3 and T4) and ground electrodes. The experiments were divided into 3 parts. The first part, no-odor were recorded EEG activity for 10 minutes as a baseline. The second part, subject was exposure to the water for 10 minutes as during inhalation. The last part, the water was dispersed and assessed EEG activity for 10 minutes as after inhalation.

Other: Pure water

Interventions

Aromatherapy OTHER

Subject will assigned inhale aromatherapy

Aromatherapy

Pure water OTHER

Subject will assigned inhale Pure water

Pure water

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• \> 18 years old

You may not qualify if:

• excessive nasal congestion
• neurological disorders prior to participation in the experiment

Sponsors & Collaborators

• University of Phayao: lead

Study Sites (2)

Surasak Saokaew

Muang, Changwat Phayao, 56000, Thailand

Location

University of Phayao

Muang, Changwat Phayao, 56000, Thailand

Location

MeSH Terms

Interventions

Aromatherapy

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Phytotherapy; Sensory Art Therapies; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Surasak Saokaew, PhD

  University of Phayao

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Co-Principal Investigator

Study Record Dates

• First Submitted: September 28, 2011
• First Posted: September 30, 2011
• Study Start: September 1, 2011
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2014
• Last Updated: May 27, 2015

Record last verified: 2015-05

Locations

TH (2)