Sleep Patterns in Children With and Without Juvenile Idiopathic Arthritis

NCT01434082 | Unknown DMC

• 2 other identifiers: JIA1R01NR012734-01
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators are doing this study to look at sleep problems, daytime sleepiness, and thinking and behavior patterns in children with arthritis and in children without arthritis. Arthritis is a problem with joints. Some children have arthritis and some children do not have arthritis. Sleep disordered breathing is a sleeping problem in which some children snore and have pauses in their breathing during sleep. It is associated with not enough or fragmented sleep, poor school performance, problems paying attention, and behavior problems. The investigators do not know how many children with arthritis have sleep problems, and how it is linked to daytime sleepiness and children's learning, and behavior patterns compared to children without arthritis. The investigators need to study both children with arthritis and children without arthritis to learn more about these connections and to understand if they are the same or different in children with arthritis and in children without arthritis.

Conditions

Juvenile Idiopathic Arthritis

Keywords

sleep; school-age children; Children with and without arthritis

Outcome Measures

Primary Outcomes (1)

• Prevalence of Sleep Disordered Breathing

  3.5 years

Secondary Outcomes (1)

• Measures of Daytime Sleepiness

  3.5 years

Interventions

comparison of types of sleep disordered breathing BEHAVIORAL

comparison of types of sleep disordered breathing (primary snoring, upper airway resistance syndrome, obstructive sleep apnea) in children with and without arthritis.

Eligibility Criteria

• Age: 6 Years - 11 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

* Children with arthritis will be recruited from the Division of Pediatric Rheumatology at Seattle Children's Hospital. * Children without arthritis will be recruited from the King COunty community.

You may qualify if:

• Children
• Children with and without arthritis, 6 thru 11 years old, able to speak English
• Children with JIA not recently hospitalized for severe JIA.
• Parents
• Subject's parents or legal guardian are \> 18 years of age and able to read and speak English.
• Subject's parent or legal guardian has provided written informed consent prior to screening for this study.

You may not qualify if:

• Children
• A child with a history of/current diagnosis of a psychiatric condition meeting DSM-IV-TR (e.g. depression, bipolar disorder) that would interfere with ability to comply with protocol requirements, or give informed consent, or be expected to have disordered sleep.
• A child with acute illness such as a cold or the flu that would interfere with sleep and neurobehavioral testing.
• A chronic condition such as cancer, diabetes, or asthma which would, in the investigator's opinion, compromise the subject's ability to comply with the study requirements and interfere with ability to comply with protocol requirements.
• Children admitted to the hospital for severe JIA within the last 2 months.
• Children with a BMI \>95th percentile (defined as obesity by CDC) will be excluded because of potential impact of obesity on SDB.
• Parents
• A parent or legal guardian with a chronic condition that would compromise the parent's ability to comply with protocol requirements.

Sponsors & Collaborators

• University of Washington: lead

Study Sites (1)

University of Washington School of Nursing

Seattle, Washington, 98195, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Morning urine and saliva

MeSH Terms

Conditions

Arthritis, Juvenile

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Central Study Contacts

Teresa M Ward, PhD, RN

CONTACT

206-221-6576; teward@u.washington.edu

Audrey Hendrickson, MPH

CONTACT

206-884-7495; audrey.hendrickson@seattlechildrens.org

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, Prinicpal Investigator

Study Record Dates

• First Submitted: September 9, 2011
• First Posted: September 14, 2011
• Study Start: September 1, 2011
• Primary Completion: January 1, 2015
• Study Completion: February 1, 2015
• Last Updated: September 14, 2011

Record last verified: 2011-09

Locations

US (1)