NCT01430208

Brief Summary

Hysteroscopy is a procedure designed for the diagnosis and the treatment of intra-uterine diseases. The development of smaller hysteroscopes allowed to change the approach to the intra-uterine lesions unifying the diagnostic and operative time. Recently Gubbini et al. developed a mini-resectoscope feasible for "see\&treat" hysteroscopy. The objective of the study is to compare the new 16 Fr mini28 resectoscope by Gubbini with Traditional 22 Fr resectoscope and Bettocchi 15 Fr hysteroscope for the treatment of uterine cavitary lesions. The investigators enrolled 401 women affected by endometrial polyps and/or G0 myomas, randomly allocated to receive the treatment with traditional resectoscope (127 women), with mini-resectoscope by Gubbini (142 women) and Bettocchi hysteroscope (132 women). Operating time, distension media delivered, dismiss time and discomfort experienced were recorded.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
401

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2010

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2011

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2011

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 8, 2011

Completed
Last Updated

September 8, 2011

Status Verified

September 1, 2011

Enrollment Period

1.2 years

First QC Date

September 2, 2011

Last Update Submit

September 7, 2011

Conditions

Keywords

endometrial pathology

Outcome Measures

Primary Outcomes (1)

  • efficacy of the treatment with mini-resectoscope in comparison with the traditional hysteroscopy in the whole group of 401 patients

    Operating time (min), distension media used (ml), dismiss time (hours), patients discomfort (VAS)

    sixteen months

Secondary Outcomes (1)

  • efficacy of the treatment with mini-resectoscope in comparison with the traditional hysteroscopy in the treatment of intrauterine lesions larger than 1,5cm in diameter

    sixteen months

Study Arms (3)

mini-resectoscope

ACTIVE COMPARATOR
Procedure: resectoscopy

tradiorional resectoscope

ACTIVE COMPARATOR
Procedure: resectoscopy

bettocchi resectoscope

ACTIVE COMPARATOR
Procedure: resectoscopy

Interventions

resectoscopyPROCEDURE

hysteroscopy for myomas G0 and/or polyps

bettocchi resectoscopemini-resectoscopetradiorional resectoscope

Eligibility Criteria

Age18 Years - 75 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • women between 18-75 years of age
  • endometrial polyps and/or G0 myomas smaller than 3 cm of diameter

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Catholic university of Sacred Heart

Rome, Rome, 00168, Italy

Location

Related Publications (1)

  • Ricciardi R, Lanzone A, Tagliaferri V, Di Florio C, Ricciardi L, Selvaggi L, Guido M. Using a 16-French resectoscope as an alternative device in the treatment of uterine lesions: a randomized controlled trial. Obstet Gynecol. 2012 Jul;120(1):160-5. doi: 10.1097/AOG.0b013e31825b9086.

MeSH Terms

Conditions

MyomaPolyps

Condition Hierarchy (Ancestors)

Neoplasms, Muscle TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
medical doctor

Study Record Dates

First Submitted

September 2, 2011

First Posted

September 8, 2011

Study Start

January 1, 2010

Primary Completion

April 1, 2011

Study Completion

June 1, 2011

Last Updated

September 8, 2011

Record last verified: 2011-09

Locations