Berlin Beat of Running Study

NCT01428778 | Completed

• 2 other identifiers: Berlin BeatEA4/042/11
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.

Conditions

Cardiac Arrhythmia; Brain Lesion; Stroke

Keywords

Marathon running; Brain MRI; ECG recording; Blood tests

Outcome Measures

Primary Outcomes (1)

• Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording

  During ECG recording

  Up to 48 hours after the marathon race.

Secondary Outcomes (1)

• Rate of (clinically silent) cerebral lesions detected by 3 Tesla brain MRI.

  3 days

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Experienced marathon runners

You may qualify if:

• Age 35-65 years
• at least 2 marathon runs within the last 5 years
• weekly running of at least 40 km

You may not qualify if:

• Known cardiac arrhythmia or prior stroke
• contraindication for MRI.

Sponsors & Collaborators

• Charite University, Berlin, Germany: lead
• Center for Stroke Research Berlin: collaborator
• Medical Institute BMW-Berlin Marathon, Berlin, Germany: collaborator

Study Sites (1)

Center for Stroke Research Berlin

Berlin, Germany

Location

Related Publications (2)

• Herm J, Topper A, Wutzler A, Kunze C, Krull M, Brechtel L, Lock J, Fiebach JB, Heuschmann PU, Haverkamp W, Endres M, Jungehulsing GJ, Haeusler KG. Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study. BMJ Open. 2017 Aug 3;7(8):e015798. doi: 10.1136/bmjopen-2016-015798.

  PMID: 28775185 DERIVED

• Haeusler KG, Herm J, Kunze C, Krull M, Brechtel L, Lock J, Hohenhaus M, Heuschmann PU, Fiebach JB, Haverkamp W, Endres M, Jungehulsing GJ. Rate of cardiac arrhythmias and silent brain lesions in experienced marathon runners: rationale, design and baseline data of the Berlin Beat of Running study. BMC Cardiovasc Disord. 2012 Aug 31;12:69. doi: 10.1186/1471-2261-12-69.

  PMID: 22938148 DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Whole blood samples

MeSH Terms

Conditions

Arrhythmias, Cardiac; Stroke

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases

Study Officials

• Karl Georg Haeusler, MD

  Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Germany.

  PRINCIPAL INVESTIGATOR

• Matthias Endres, MD

  Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Germany

  STUDY CHAIR

• Wilhelm Haverkamp, MD

  Departement of Cardiology, Campus Virchow, Charité - Universitätsmedizin Berlin, Germany

  STUDY CHAIR

• Matthias Kruell, MD

  Medical Institute BMW-Berlin Marathon

  STUDY CHAIR

• Peter U Heuschmann, MD

  Center for Stroke Research Berlin

  STUDY CHAIR

• Gerhard Jan Jungehuelsing, MD

  Center for Stroke Research Berlin

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: August 31, 2011
• First Posted: September 5, 2011
• Study Start: September 1, 2011
• Primary Completion: September 1, 2012
• Study Completion: September 1, 2012
• Last Updated: November 8, 2016

Record last verified: 2016-11

Locations

DE (1)