NCT01701713

Brief Summary

The purpose of this study is to determine the safety of transcranial direct current stimulation in aphasia therapy in acute and post-acute stroke.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started Jun 2009

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2009

Completed
3.3 years until next milestone

First Submitted

Initial submission to the registry

September 26, 2012

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 5, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2013

Completed
Last Updated

October 8, 2012

Status Verified

October 1, 2012

Enrollment Period

4 years

First QC Date

September 26, 2012

Last Update Submit

October 5, 2012

Conditions

Keywords

TDCSSTROKEAPHASIANAMING

Outcome Measures

Primary Outcomes (1)

  • skin irritation

    2 months

Secondary Outcomes (1)

  • Improved language

    2 months

Study Arms (2)

TDCS - DKI ED2011

EXPERIMENTAL

TDCS with DKI ED2011 session is followed by a behavioral naming therapy with different cues

Device: DKI ED2011

Sham-TDCS

SHAM COMPARATOR

Sham-TDCS session is followed by a behavioral naming therapy with different cues

Device: Sham-TDCS

Interventions

TDCS - DKI ED2011
Sham-TDCSDEVICE
Sham-TDCS

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • first media stroke
  • language impairment
  • informed consent
  • right handedness
  • NIHSS \< 20

You may not qualify if:

  • previous Epilepsy oder epileptogenic events
  • epilepsy typical elements in EEG
  • hypersensitive skin (head)
  • metal implants (head)
  • pace maker or other electronic implants
  • previous head/brain surgery
  • medication reducing seizure threshold
  • previous psychiatric events

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Brandenburg Klinik Bernau

Bernau bei Berlin, Brandenburg, 16321, Germany

RECRUITING

Charité, Campus Benjamin Franklin, Dep. of Neurology

Berlin, State of Berlin, 12200, Germany

COMPLETED

MeSH Terms

Conditions

StrokeAphasia

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesSpeech DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Gerhard J Jungehuelsing, MD

    Center for Stroke Research Berlin (CSB), Charité

    PRINCIPAL INVESTIGATOR
  • Michael Joebges, Prof. MD

    Brandenburgklinik Bernau

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gerhard J Jungehuelsing, MD

CONTACT

Isabell Wartenburger, Prof. MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

September 26, 2012

First Posted

October 5, 2012

Study Start

June 1, 2009

Primary Completion

June 1, 2013

Study Completion

June 1, 2013

Last Updated

October 8, 2012

Record last verified: 2012-10

Locations