NCT01380171

Brief Summary

Children who are born with cleft palate need surgery in order to correct the problem. The surgery is needed because the defect allows food to leak into the nose. It also causes the patient to be unable to speak correctly, producing a problematic nasal sound. Sometimes the first surgery does not completely correct the problem and a second surgery is needed. Looking at the records of patients who have had corrective surgeries done in the past would allow the surgeons to improve their success rate and reduce the need for secondary surgeries. It would also create greater patient safety and reduce cost for families.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,295

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2007

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2007

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2009

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

May 24, 2010

Completed
1.1 years until next milestone

First Posted

Study publicly available on registry

June 27, 2011

Completed
Last Updated

June 27, 2011

Status Verified

June 1, 2011

Enrollment Period

2.8 years

First QC Date

May 24, 2010

Last Update Submit

June 24, 2011

Conditions

Study Arms (1)

Cleft lip/palate

Patients who have had surgical intervention for cleft lip/palate since 1998 at Children's Healthcare of Atlanta at the Center for Craniofacial Disorders

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

1295 patients with cleft lip/palate that have been treated since 1998 at the Center for Craniofacial Disorders at Children's Healthcare of Atlanta on the Scottish Rite campus.

You may qualify if:

  • Children operated on by surgeons at the Center for Craniofacial Disorders
  • Have a diagnosis of cleft lip/palate
  • Children with a syndrome in addition to cleft lip/palate will be evaluated in a different category

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's Healthcare of Atlanta at Scottish Rite

Atlanta, Georgia, 30342, United States

Location

Related Links

MeSH Terms

Conditions

Cleft LipCleft Palate

Condition Hierarchy (Ancestors)

Lip DiseasesMouth DiseasesStomatognathic DiseasesMouth AbnormalitiesStomatognathic System AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesJaw AbnormalitiesJaw DiseasesMusculoskeletal DiseasesMaxillofacial AbnormalitiesCraniofacial AbnormalitiesMusculoskeletal Abnormalities

Study Officials

  • John Riski, PhD

    Children's Healthcare of Atlanta

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 24, 2010

First Posted

June 27, 2011

Study Start

February 1, 2007

Primary Completion

November 1, 2009

Study Completion

December 1, 2009

Last Updated

June 27, 2011

Record last verified: 2011-06

Locations