Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program
1 other identifier
interventional
360
1 country
1
Brief Summary
Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly indicated. Although commercially available media have commonly been used in most IVF programs worldwide, there are several advantages to the use of in-house synthetic sequential media at IVF laboratories. First, the results of quality control should be reliable due to a stringent protocol setting-up. Second, any direct supplementations or deletions of specific components are feasible to obtain good quality embryos and high pregnancy rates since those components can be defined. Finally, dependence on commercially available media diminishes so that the laboratory can more easily accommodate unexpected situations or problems, such as a sudden increase in IVF patients. Therefore, the present study was conducted to compare the efficacy of in-house MRC media in the human IVF-embryo transfer (ET) program to that of commercially available media.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Nov 2009
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2010
CompletedFirst Submitted
Initial submission to the registry
May 17, 2011
CompletedFirst Posted
Study publicly available on registry
May 19, 2011
CompletedMay 19, 2011
October 1, 2009
10 months
May 17, 2011
May 18, 2011
Conditions
Outcome Measures
Primary Outcomes (1)
Embryo Quality
3 Days
Secondary Outcomes (1)
Pregnancy and Implantation rates
2 months
Study Arms (2)
MRC media
EXPERIMENTALUse MRC media in the human IVF-ET program
Sydney IVF media
ACTIVE COMPARATORUse Sydney IVF media in the human IVF-ET program
Interventions
Eligibility Criteria
You may qualify if:
- Patients undergoing IVF treatment in our clinic during study period
You may not qualify if:
- Females older than 40 years
- Patients showed fertilization failure
- Patients with less than two 2PN embryos
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Maria Fertility Hospital
Seoul, 130-812, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jeong Yoon, M.S.
Maria Fertility Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
May 17, 2011
First Posted
May 19, 2011
Study Start
November 1, 2009
Primary Completion
September 1, 2010
Study Completion
October 1, 2010
Last Updated
May 19, 2011
Record last verified: 2009-10