NCT01309906

Brief Summary

The objective of this study is to determine the clinical feasibility and to evaluate the product performance of an investigational contact lens.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2010

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2011

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2011

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 4, 2011

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 7, 2011

Completed
9.6 years until next milestone

Results Posted

Study results publicly available

October 22, 2020

Completed
Last Updated

October 22, 2020

Status Verified

September 1, 2020

Enrollment Period

1 month

First QC Date

March 4, 2011

Results QC Date

August 21, 2020

Last Update Submit

September 29, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual Acuity

    Visual acuity was assessed by distance high contrast logarithm of the minimum angle of resolution (logMAR).

    At 1 week follow up

Secondary Outcomes (2)

  • Percentage of Eyes With > Grade 2 Slit Lamp Findings

    At 1 week follow up

  • Symptoms and Complaints

    At 1 week follow up

Study Arms (2)

Investigational lens

EXPERIMENTAL

Bausch \& Lomb investigational silicone hydrogel lens

Device: Investigational lens

Air Optix Aqua lens

ACTIVE COMPARATOR

Ciba Vision Air Optix Aqua contact lens

Device: Air Optix Aqua lens

Interventions

Bausch \& Lomb investigational silicone hydrogel contact lens worn on a daily wear basis for 1 week.

Investigational lens

Ciba Visions Air Optix Aqua contact lens, worn on a daily wear basis for 1 week.

Air Optix Aqua lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Be myopic and require lens correction in each eye.
  • Be adapted wearers of soft contact lenses, wear a lens in each eye, and each lens must be of the same manufacture and brand.

You may not qualify if:

  • Any systemic disease affecting ocular health.
  • Using any systemic or topical medications that will affect ocular physiology or lens performance.
  • An active ocular disease, any corneal infiltrative response or are using any ocular medications.
  • Any "Present" finding during the slit lamp examination that, in the Investigator's judgment, interferes with contact lens wear.
  • Allergic to any component in the study care products.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb Incorporated

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Study Director
Organization
Bausch Health

Study Officials

  • Tara Vaz, OD

    Bausch & Lomb Incorporated

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 4, 2011

First Posted

March 7, 2011

Study Start

December 1, 2010

Primary Completion

January 1, 2011

Study Completion

February 1, 2011

Last Updated

October 22, 2020

Results First Posted

October 22, 2020

Record last verified: 2020-09

Locations