NCT01309893

Brief Summary

The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2010

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2011

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2011

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 4, 2011

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 7, 2011

Completed
3.7 years until next milestone

Results Posted

Study results publicly available

November 24, 2014

Completed
Last Updated

November 24, 2014

Status Verified

November 1, 2014

Enrollment Period

1 month

First QC Date

March 4, 2011

Results QC Date

November 4, 2014

Last Update Submit

November 20, 2014

Conditions

Keywords

Contact lens

Outcome Measures

Primary Outcomes (1)

  • Distance High Contrast logMAR Visual Acuity at 1 Week

    Mean difference in distance high contrast logMAR over all lens VAs (visual acuity) from Baseline and 1 Week

    Baseline & 1 week

Secondary Outcomes (2)

  • Slit Lamp Findings ≥ Grade 2

    1 week

  • Overall Comfort

    1 week

Study Arms (2)

Investigational Lens

EXPERIMENTAL

Bausch \& Lomb investigational silicone hydrogel contact lens for 1 week; then issued Air Optix Aqua Lens for 1 week.

Device: Investigational LensDevice: Air Optix Aqua lens

Air Optix Aqua Lens

ACTIVE COMPARATOR

Ciba Vision Air Optix Aqua contact lens for 1 week; then issued Investigational Lens for 1 week.

Device: Investigational LensDevice: Air Optix Aqua lens

Interventions

Lenses worn on a daily wear basis for one week

Air Optix Aqua LensInvestigational Lens

Lenses worn on a daily wear basis for one week

Air Optix Aqua LensInvestigational Lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Be myopic and require lens correction from -0.50 D to -5.50 D in each eye.

You may not qualify if:

  • Any systemic disease affecting ocular health.
  • Using any systemic or topical medications that will affect ocular physiology or lens performance.
  • An active ocular disease, any corneal infiltrative response or are using any ocular medications.
  • Any "Present" finding during the slit lamp examination that, in the Investigator's judgment, interferes with contact lens wear.
  • Allergic to any component in the study care products.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch & Lomb

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Dr. Robert Steffen
Organization
Bausch & Lomb

Study Officials

  • Robert Steffen, OD, MS

    Bausch & Lomb Incorporated

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 4, 2011

First Posted

March 7, 2011

Study Start

December 1, 2010

Primary Completion

January 1, 2011

Study Completion

February 1, 2011

Last Updated

November 24, 2014

Results First Posted

November 24, 2014

Record last verified: 2014-11

Locations