NCT01295268

Brief Summary

The goal of this study is to determine if vulvar (external female genitalia) pain is decreased with emu oil over a similar placebo oil (no active ingredient) by using measurement devices, examinations, and questionnaires. Topical emu oil has not been scientifically studied for this condition yet, but related reports show no significant side effects or potential benefits. A total of 30 women will participate in the study at William Beaumont Hospital, Royal Oak.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2011

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

February 10, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 14, 2011

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

January 25, 2017

Status Verified

May 1, 2012

Enrollment Period

6 months

First QC Date

February 10, 2011

Last Update Submit

January 23, 2017

Conditions

Keywords

Vulvar painVulvodyniaVestibulodyniaVulvar vestibulitis

Outcome Measures

Primary Outcomes (1)

  • The change in the Global Response Assessment (GRA) for vulvar pain.

    Those "moderately" or "markedly" improved on the GRA are responders

    After 1 month of intervention

Secondary Outcomes (1)

  • The change in vulvar pain levels

    After 1 month of intervention

Study Arms (2)

Emu Oil

ACTIVE COMPARATOR
Other: Emu Oil

inert oil

PLACEBO COMPARATOR
Other: Inert oil

Interventions

Emu OilOTHER

Subjects will apply a specified amount of emu oil daily to area.

Emu Oil

A specified amount of inert oil will be applied daily to area.

inert oil

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women with vulvar pain upon q-tip exam of \> 3/10 at 2 or more sites tested.
  • Age 18 or older.
  • Capable of giving informed consent.
  • Capable and willing to follow all study procedures.

You may not qualify if:

  • Pregnant women or those intending to become pregnant during the study period.
  • Vaginitis (may be treated, then tested later).
  • Vulvar disease (other than vulvodynia)-lichen planus, lichen sclerosis, neoplasia, tissue damage due to radiation.
  • The subject is deemed unsuitable for enrollment by the investigators based on their history or physical examination.
  • Neuropathy.
  • Currently in pelvic floor physical therapy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Beaumont Women's Urology Center

Royal Oak, Michigan, 48073, United States

Location

MeSH Terms

Conditions

VulvodyniaVulvar Vestibulitis

Interventions

emu Oil

Condition Hierarchy (Ancestors)

Vulvar DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital DiseasesVulvitis

Study Officials

  • Donna J Carrico, WHNP, MS

    Corewell Health East

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2011

First Posted

February 14, 2011

Study Start

February 1, 2011

Primary Completion

August 1, 2011

Study Completion

August 1, 2011

Last Updated

January 25, 2017

Record last verified: 2012-05

Locations