NCT01283165

Brief Summary

The main objective of the project was to determine the effect of integrated school based deworming and health education on prevalence and morbidity due to co-infection infection with schistosomiasis, STHs and malaria among primary school age children living in rural and farming areas in Zimbabwe There is need for regular school based de-worming and health education programs for the helminths-Plasmodium co-infections in primary schoolchildren living in rural and commercial farming areas in Zimbabwe

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,303

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2003

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2003

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2006

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2006

Completed
4.2 years until next milestone

First Submitted

Initial submission to the registry

January 24, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 25, 2011

Completed
Last Updated

November 10, 2011

Status Verified

January 1, 2003

Enrollment Period

3.2 years

First QC Date

January 24, 2011

Last Update Submit

November 9, 2011

Conditions

Integrated Control of Malaria and Polyparasitism

Keywords

health educationPolyparasitismschool based deworming programintegrated control of parasites

Outcome Measures

Primary Outcomes (1)

  • This study was conducted to determine the prevalence of polyparasitism among primary school children living in rural and commercial farming areas in Zimbabwe.

    This study was conducted to determine the prevalence of polyparasitism, the impact of polyparasitism on anaemia, the effect of combined school based treatment for STHs, schistosomiasis, health education and prompt malaria treatment on anaemia and prevalence of polyparasitism in primary school children.

    3 years

Secondary Outcomes (1)

  • Impact of school based parasite treatment and health education intervention.

    3 years

Study Arms (1)

health education

This was an intervention follow up Knowledge Attitude and Practice study that investigated the distribution of polyparasitism with schistosomiasis, STHs and P. falciparum among primary schoolchildren.

Behavioral: Health education intervention

Interventions

Health education interventionBEHAVIORAL

Health education was conducted in two ways. (1) Teachers were taught how to use the flip chart that contained health education material about parasites. The lessons were done during free periods as this intervention had not been formally fitted into the school syllabus. (2) The research team provided health education to school children. Focus group discussions were conducted by the research team with school children all assembled outside their classes. Health education leaflets were distributed to all school children at the school. Children were asked to share the health information with their friends and families.

Also known as: Knowledge Attitude and Practice intervention
health education

Eligibility Criteria

Age5 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Primary school going children living in rural and commercial farming areas

You may qualify if:

  • all school children at the primary schools

You may not qualify if:

  • Very sick with known TB or HIV infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Biochemistry Department University of Zimbabwe

Harare, Zimbabwe

Location

Related Publications (3)

  • Midzi N, Mtapuri-Zinyowera S, Mapingure MP, Sangweme D, Chirehwa MT, Brouwer KC, Mudzori J, Hlerema G, Mutapi F, Kumar N, Mduluza T. Consequences of polyparasitism on anaemia among primary school children in Zimbabwe. Acta Trop. 2010 Jul-Aug;115(1-2):103-11. doi: 10.1016/j.actatropica.2010.02.010. Epub 2010 Feb 20.

    PMID: 20175980RESULT

  • Midzi N, Sangweme D, Zinyowera S, Mapingure MP, Brouwer KC, Munatsi A, Mutapi F, Mudzori J, Kumar N, Woelk G, Mduluza T. The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe. Trans R Soc Trop Med Hyg. 2008 Oct;102(10):1039-45. doi: 10.1016/j.trstmh.2008.05.024. Epub 2008 Jul 24.

    PMID: 18656215RESULT

  • Midzi N, Sangweme D, Zinyowera S, Mapingure MP, Brouwer KC, Kumar N, Mutapi F, Woelk G, Mduluza T. Efficacy and side effects of praziquantel treatment against Schistosoma haematobium infection among primary school children in Zimbabwe. Trans R Soc Trop Med Hyg. 2008 Aug;102(8):759-66. doi: 10.1016/j.trstmh.2008.03.010. Epub 2008 May 16.

    PMID: 18486169RESULT

Related Links

MeSH Terms

Conditions

Health Education

Condition Hierarchy (Ancestors)

Adherence InterventionsMedication AdherencePatient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Takafira Mduluza, PhD

    University of Zimbabwe

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 24, 2011

First Posted

January 25, 2011

Study Start

April 1, 2003

Primary Completion

June 1, 2006

Study Completion

December 1, 2006

Last Updated

November 10, 2011

Record last verified: 2003-01

Locations

ZI(1)