Research in Autism: Parent Intervention

NCT01258465 | Completed DMC

• 1 other identifier: MH39434
• Study Type: interventional
• Target: 39
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model. In one condition, randomly assigned children were provided with an intervention that typically results in acquisition of expressive words in a large percentage of children diagnosed as having autism, using a well-documented manualized intervention focused on verbal expressive communication only (Pivotal Response Training, PRT). In the other condi¬tion, randomly assigned children received a widely used intervention on the same social communication functions using a well-documented manualized augmentative system of intervention (Picture Exchange Communica¬tion System, PECS) that has been reported to produce verbal and nonverbal communication in large percentages of children diagnosed with autism. Children in the two conditions were compared for development of verbal and nonverbal communication, changes in disruptive behavior, changes in symptoms of autism, and general adaptive behavior gains. In addition, parent satisfaction and stress measures were gathered in order to assess the effects of each intervention on family functioning.

Conditions

Autistic Disorder

Keywords

Communication; Pivotal Response Training; Picture Exchange Communication System

Outcome Measures

Primary Outcomes (1)

• Mullen Scales of Early Learning

  23 weeks with three months follow-up

Secondary Outcomes (1)

• Vineland Adaptive Behavior Scales

  23 weeks and 3 month follow up

Study Arms (2)

Pivotal Response Training

ACTIVE COMPARATOR

A naturalistic behavioral intervention designed to facilitate verbal communication.

Behavioral: Pivotal Response Training; Behavioral: Picture Exchange Communication System

Picture Exchange Communication System

ACTIVE COMPARATOR

Pictorially-based behavioral protocol designed to facilitate communication via picture icons.

Behavioral: Picture Exchange Communication System

Interventions

Pivotal Response Training BEHAVIORAL

Naturalistic behavioral protocol designed to teach vocal communication.

Pivotal Response Training

Picture Exchange Communication System BEHAVIORAL

Pictorially-based behavioral protocol designed to teach communication to nonverbal children via pictures icons.

Picture Exchange Communication System; Pivotal Response Training

Eligibility Criteria

• Age: 24 Months - 47 Months
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Diagnosis of Autistic Disorder or At Risk of Autistic Disorder
• Age 2-0 to 3-11 years of age
• Use of fewer than 10 functional words at intake

You may not qualify if:

• Primary diagnosis of mental retardation
• Neurologic pathology (e.g., PKU, encephalitis, brain trauma)
• Major sensory impairment

Sponsors & Collaborators

• University of California, San Diego: lead

Study Sites (2)

University of California, San Diego Psychology Department

La Jolla, California, 92093-0109, United States

Location

University of California, Santa Barbara, School of Education, Department of Clinical, Counseling, and School Psychology

Santa Barbara, California, 93108, United States

Location

MeSH Terms

Conditions

Autistic Disorder; Communication

Condition Hierarchy (Ancestors)

Autism Spectrum Disorder; Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders; Behavior

Study Officials

• Laura E Schreibman, Ph.D.

  University of California, San Diego

  PRINCIPAL INVESTIGATOR

• Robert L Koegel, Ph.D.

  University of California, Santa Barbara

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 10, 2010
• First Posted: December 13, 2010
• Study Start: January 1, 2005
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: December 13, 2010

Record last verified: 2010-12

Locations

US (2)