The Variation of Movement Related Cortical Potential, Cortico-cortical Inhibition, and Motor Evoked Potential in Intracerebral Implantation of Antologous Peripheral Blood Stem Cells(CD34)in Old Ischemic Stroke

NCT01239602 | Unknown

• 1 other identifier: DMR99-IRB-200
• Study Type: observational
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

Stem cell theray in old stroke patients is a study to treat stroke patients approved before in our hospital. We recruit these patients who received stem cell therapy and completed the study. We adopted movement-related cortical potential,and cortico-cortical inhibition to assess the stroke patients with or without stem cell therapy. Further analyzing the correlation of the motor related cortical potential and cortico-cortical inhibition among them. We wanted to find out if there are changes in cortical excitability in subjects with chronic stroke after stem cell therapy.

Conditions

Stroke

Keywords

changes in cortical excitability in subjects with chronic stroke after stem cell therapy

Study Arms (3)

Normal control

with Stem cell therapy plus G-CSF

G-CSF along

Eligibility Criteria

• Age: 30 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

36 patients suffered from old cerebral infarction (middle cerebral artery territory as documented on the T2 weight image \[T2WI\] of MRI) between 6 months and 5 years of onset who had initial scores on the National Institute of Health stroke scale (NIHSS) of between 9 and 20.

You may qualify if:

• old cerebral infarction (middle cerebral artery territory as documented on the T2 weight image \[T2WI\] of MRI) 2.between 6 months and 5 years of onset 3.National Institute of Health stroke scale (NIHSS) of between 9 and 20.

You may not qualify if:

• Seizure history 2. Pacemaker insertion

Sponsors & Collaborators

• China Medical University Hospital: lead

Study Sites (1)

China Medical University Hospital

Taichung, Taiwan, 404, Taiwan

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: November 10, 2010
• First Posted: November 11, 2010
• Study Start: October 1, 2010
• Primary Completion: October 1, 2010
• Study Completion: October 1, 2010
• Last Updated: November 11, 2010

Record last verified: 2010-11

Locations

TW (1)