NCT01216319

Brief Summary

Patients with a desire for nipple reconstruction following breast cancer and breast reconstruction will receive a surgical procedure to reconstruct one or both nipples utilizing the COOK Biodesign® Nipple Reconstruction Cylinder.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable breast-cancer

Timeline
Completed

Started Sep 2011

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 5, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 7, 2010

Completed
11 months until next milestone

Study Start

First participant enrolled

September 1, 2011

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2014

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

May 15, 2015

Completed
Last Updated

June 23, 2016

Status Verified

May 1, 2016

Enrollment Period

2.6 years

First QC Date

October 5, 2010

Results QC Date

April 30, 2015

Last Update Submit

May 19, 2016

Conditions

Keywords

BiodesignNipple ReconstructionBreast CancerMastectomy

Outcome Measures

Primary Outcomes (1)

  • Percent Nipple Projection at 12 Months Compared to Baseline (1 Week Post-procedure)

    12 months

Secondary Outcomes (1)

  • Rate of Patient Satisfaction

    12 months

Study Arms (1)

Nipple Reconstruction Cylinder

EXPERIMENTAL
Device: Nipple reconstruction

Interventions

Biodesign® Nipple Reconstruction Cylinder

Also known as: Biodesign
Nipple Reconstruction Cylinder

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient presents with a history of breast cancer, having previously completed either uni- or bi-lateral breast removal and reconstruction.
  • Patient presents with a desire to obtain nipple reconstruction
  • Patient is at least 18 years of age

You may not qualify if:

  • Patient is not medically fit enough for surgery under local anesthesia
  • Patient is currently smoking, using tobacco products, or nicotine products (i.e. patch, gum, or nasal spray)
  • Patient is pregnant, breastfeeding or planning further pregnancy during the study period
  • Patient has physical allergies or cultural objections to the receipt of porcine products

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Stanford University School of Medicine

Stanford, California, 94305, United States

Location

Park Meadows Cosmetic Surgery

Lone Tree, Colorado, 80124, United States

Location

Mercy Medical Center

Baltimore, Maryland, 21202, United States

Location

Sanford Clinic Plastic and Reconstructive Surgery

Sioux Falls, South Dakota, 57105, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Results Point of Contact

Title
Jason Hodde, Clinical Affairs Manager
Organization
Cook Biotech Incorporated

Study Officials

  • Geoffrey Gurtner, MD

    Stanford University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 5, 2010

First Posted

October 7, 2010

Study Start

September 1, 2011

Primary Completion

April 1, 2014

Study Completion

April 1, 2014

Last Updated

June 23, 2016

Results First Posted

May 15, 2015

Record last verified: 2016-05

Locations