NCT01208272

Brief Summary

Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
162

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Apr 1994

Longer than P75 for phase_1

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1994

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 1998

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 1999

Completed
11.5 years until next milestone

First Submitted

Initial submission to the registry

August 31, 2010

Completed
23 days until next milestone

First Posted

Study publicly available on registry

September 23, 2010

Completed
Last Updated

September 23, 2010

Status Verified

September 1, 2010

Enrollment Period

3.9 years

First QC Date

August 31, 2010

Last Update Submit

September 22, 2010

Conditions

Binge Eating DisorderCognitive Therapy/MethodsMental Disorders/EpidemiologyObesity/EpidemiologyObesity/Therapy

Keywords

Body Mass IndexBulimia/therapyComorbidityInterpersonal RelationsPsychotherapy/methods

Outcome Measures

Primary Outcomes (1)

  • To investigate the short and long-term efficacy of two treatments for binge eating among the overweight: Group Cognitive-Behavior (CBT) and Group Interpersonal Therapy (IPT).

    Assessments of binge eating and associated eating disorder paychopathology, general psychological functioning, and weight occurred before treatment, at post treatment, and at 4-month intervals up to 12 months following treatment.

Study Arms (1)

Binge Eating Disorder/Therapy

EXPERIMENTAL
Behavioral: Cognitive Behavioral Therapy (CBT)Behavioral: Interpersonal Therapy (IPT)

Interventions

Cognitive Behavioral Therapy (CBT)BEHAVIORAL
Binge Eating Disorder/Therapy
Interpersonal Therapy (IPT)BEHAVIORAL
Binge Eating Disorder/Therapy

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • DSM-IV research criteria for binge-eating disorder
  • Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
  • Marked stress regarding binge eating
  • At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
  • years old
  • Body mass index, 27-48 kg/m squared

You may not qualify if:

  • Pregnant or planning to become pregnant
  • Taking weight-affecting or psychotropic medications
  • Psychiatric conditions warranting immediate treatment
  • Current enrollment in psychotherapy or a weight loss program

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Yale University

New Haaven, Connecticut, 06511-3516, United States

Location

Yale University

New Haven, Connecticut, 06511-3516, United States

Location

Related Publications (2)

  • Wilfley DE, Welch RR, Stein RI, Spurrell EB, Cohen LR, Saelens BE, Dounchis JZ, Frank MA, Wiseman CV, Matt GE. A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch Gen Psychiatry. 2002 Aug;59(8):713-21. doi: 10.1001/archpsyc.59.8.713.

    PMID: 12150647RESULT

  • Hilbert A, Bishop ME, Stein RI, Tanofsky-Kraff M, Swenson AK, Welch RR, Wilfley DE. Long-term efficacy of psychological treatments for binge eating disorder. Br J Psychiatry. 2012 Mar;200(3):232-7. doi: 10.1192/bjp.bp.110.089664. Epub 2012 Jan 26.

    PMID: 22282429DERIVED

MeSH Terms

Conditions

Binge-Eating DisorderMental DisordersObesityBulimia

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Feeding and Eating DisordersOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsHyperphagiaSigns and Symptoms, Digestive

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Denise E Wilfley, Ph.D.

    Washington University School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 31, 2010

First Posted

September 23, 2010

Study Start

April 1, 1994

Primary Completion

March 1, 1998

Study Completion

March 1, 1999

Last Updated

September 23, 2010

Record last verified: 2010-09

Locations

US(2)