Optimal Duration of Early Intervention for Psychosis
Community Case Management for Early Psychosis: is Two Year an Optimal Duration? A Randomized Controlled Study
1 other identifier
interventional
160
1 country
1
Brief Summary
A total of 160 subjects, who aged 18-35 and had completed the first 2 years of case management in the EASY programme will be randomized in 1:1 ratio into either (1) receiving an additional year of case management, or (2) terminating case management for the next 12 months. The current study aims to investigate whether an additional year of case management in year 3 will confer additional benefits in outcome, in terms of functioning, symptoms, quality of life and health economics.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jul 2010
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2010
CompletedFirst Submitted
Initial submission to the registry
September 13, 2010
CompletedFirst Posted
Study publicly available on registry
September 15, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2012
CompletedSeptember 15, 2010
September 1, 2010
1.9 years
September 13, 2010
September 13, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Functioning (social and occupational)
baseline, 12-month
Secondary Outcomes (1)
Symptoms, quality of life and health economics
baseline, 12-month
Study Arms (2)
Case Management (1 year)
EXPERIMENTALStandard Care (1 year)
NO INTERVENTIONInterventions
Community case management for psychosis by designated key-worker according to specified protocol
Eligibility Criteria
You may qualify if:
- DSM-IV diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, brief psychotic disorder, psychosis not otherwise specified or delusional disorder
- Received EASY service for 2 years following a first-episode psychosis
- Cantonese-speaking Chinese
- Ability to understand the study and to provide written informed consent
You may not qualify if:
- Organic brain disorder
- Known history of intellectual disability
- Drug-induced psychosis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The University of Hong Konglead
- Queen Mary Hospital, Hong Kongcollaborator
- Pamela Youde Nethersole Eastern Hospitalcollaborator
- Kwai Chung Hospitalcollaborator
Study Sites (1)
The University of Hong Kong
Hong Kong, China
Related Publications (1)
Chang WC, Kwong VWY, Lau ESK, So HC, Wong CSM, Chan GHK, Jim OTT, Hui CLM, Chan SKW, Lee EHM, Chen EYH. Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis. Br J Psychiatry. 2017 Jul;211(1):37-44. doi: 10.1192/bjp.bp.117.198929. Epub 2017 Apr 6.
PMID: 28385705DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Eric YH Chen, MD
The University of Hong Kong
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 13, 2010
First Posted
September 15, 2010
Study Start
July 1, 2010
Primary Completion
June 1, 2012
Study Completion
June 1, 2012
Last Updated
September 15, 2010
Record last verified: 2010-09