Clinical Comparison Between Two Surgical Techniques for the Treatment of Gingival Recessions

NCT01175720 | Completed

• 1 other identifier: lga030183
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to test a surgical technique for the treatment of gingival recessions. The hypothesis of the study is to promote greater root coverage and better healing.

Conditions

Gingival Recession

Keywords

gingival recession; acellular dermal matrix graft; root coverage

Outcome Measures

Primary Outcomes (1)

• Percentage of root coverage

  Clinical parameters will be assessed after 6 months of surgical procedures.

  6 months

Secondary Outcomes (1)

• Keratinized Tissue

  6 months

Study Arms (1)

test and control

EXPERIMENTAL

The test and control technique will be tested in a split-mouth design.

Procedure: Periodontal surgery to gingival recessions

Interventions

Periodontal surgery to gingival recessions PROCEDURE

Test and control technique to treat gingival recessions.

test and control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Recession defects are Miller's class I or II and do not vary more or equal than 3 mm
• Main complaint aesthetic issues or dentine hypersensitivity
• The patient must be a candidate for bilateral root coverage procedure
• Patient shows sufficient plaque control (FMPS \< 20%)
• The patient is able to comply with the study-related procedures such as exercising good oral hygiene and attending all follow-up procedures
• The patient is able to fully understand the nature of the proposed surgery and is able to provide a signed informed consent

You may not qualify if:

• Smokers
• Systemic diseases
• Pregnants or lactating
• Periodontal disease
• General contraindications for dental and/or surgical treatment are present
• The patient has a history of malignancy, radiotherapy, or chemotherapy for malignancy within the past five years
• The patient is taking medications or having treatments which have an effect on mucosal healing in general (e.g. steroids, large doses of anti-inflammatory drugs)

Sponsors & Collaborators

• University of Sao Paulo: lead
• Fundação de Amparo à Pesquisa do Estado de São Paulo: collaborator

Study Sites (1)

Faculty of Dentistry of Ribeirão Preto USP

Ribeirão Preto, São Paulo, 14040-904, Brazil

Location

Related Publications (1)

• Ayub LG, Ramos UD, Reino DM, Grisi MF, Taba M Jr, Souza SL, Palioto DB, Novaes AB Jr. A Randomized comparative clinical study of two surgical procedures to improve root coverage with the acellular dermal matrix graft. J Clin Periodontol. 2012 Sep;39(9):871-8. doi: 10.1111/j.1600-051X.2012.01915.x. Epub 2012 Jun 19.

  PMID: 22712624 DERIVED

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Periodontal Atrophy

Study Officials

• Arthur B. Novaes Júnior, PhD

  University of Sao Paulo

  PRINCIPAL INVESTIGATOR

• Lauro G. Ayub, MSD student

  University of Sao Paulo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical comparison between two surgical techniques with acellular dermal matrix graft in the treatment of gingival recessions

Study Record Dates

• First Submitted: August 3, 2010
• First Posted: August 5, 2010
• Study Start: August 1, 2010
• Primary Completion: June 1, 2011
• Study Completion: October 1, 2011
• Last Updated: November 16, 2011

Record last verified: 2011-11

Locations

BR (1)