NCT01160809

Brief Summary

The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6,082

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Sep 2008

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2008

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

July 8, 2010

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 12, 2010

Completed
Last Updated

July 12, 2010

Status Verified

July 1, 2010

Enrollment Period

3 months

First QC Date

July 8, 2010

Last Update Submit

July 9, 2010

Conditions

MalariaMosquito RepellentLong Lasting Insecticidal Nets

Keywords

MalariaMosquito repellentLLINs

Outcome Measures

Primary Outcomes (1)

  • Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection

    The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.

Secondary Outcomes (1)

  • Household ownership and utilization of LLINs

Study Arms (1)

Mosquito repellent and LLINs group vs. LLINs group only

EXPERIMENTAL

This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).

Other: Mosquito repellent

Interventions

Mosquito repellentOTHER

Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs

Mosquito repellent and LLINs group vs. LLINs group only

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All volunteer household members

You may not qualify if:

  • Infants less than two months
  • Not in the study area

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SNNPR, Ethiopia

Awasa, Snnpr, Ethiopia

Location

Related Publications (1)

  • Deressa W, Yihdego YY, Kebede Z, Batisso E, Tekalegne A, Dagne GA. Effect of combining mosquito repellent and insecticide treated net on malaria prevalence in Southern Ethiopia: a cluster-randomised trial. Parasit Vectors. 2014 Mar 28;7:132. doi: 10.1186/1756-3305-7-132.

    PMID: 24678612DERIVED

MeSH Terms

Conditions

Malaria

Condition Hierarchy (Ancestors)

Protozoan InfectionsParasitic DiseasesInfectionsMosquito-Borne DiseasesVector Borne Diseases

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 8, 2010

First Posted

July 12, 2010

Study Start

September 1, 2008

Primary Completion

December 1, 2008

Study Completion

January 1, 2009

Last Updated

July 12, 2010

Record last verified: 2010-07

Locations

ET(1)