Malaria
862
22
41
671
Key Insights
Highlights
Success Rate
96% trial completion (above average)
Published Results
133 trials with published results (15%)
Research Maturity
671 completed trials (78% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
3.5%
30 terminated out of 862 trials
95.7%
+9.2% vs benchmark
27%
232 trials in Phase 3/4
20%
133 of 671 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 671 completed trials
Clinical Trials (862)
First-in-Human PfSPZ-LARC2 Vaccination/CHMI
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays
This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria
Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
Integrating the Guardian Spatial Emanator Within AVENIR II
A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines
Study to Assess Safety and Clinical Responses With Coartem® Baby Dispersible Tablets in Paediatric Patients Weighing 2 to <5 kg With Uncomplicated Malaria
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults
L9LS in Women of Childbearing Potential in Mali
FocaL Mass Drug Administration for Vivax Malaria Elimination
Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission
Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria
Star Homes Project 2
Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda