Malaria
860
22
42
670
Key Insights
Highlights
Success Rate
96% trial completion (above average)
Published Results
133 trials with published results (15%)
Research Maturity
670 completed trials (78% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
3.5%
30 terminated out of 860 trials
95.7%
+9.2% vs benchmark
27%
231 trials in Phase 3/4
20%
133 of 670 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 670 completed trials
Clinical Trials (860)
Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults
First-in-Human PfSPZ-LARC2 Vaccination/CHMI
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
L9LS in Women of Childbearing Potential in Mali
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays
FocaL Mass Drug Administration for Vivax Malaria Elimination
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria
Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates
Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission
Star Homes Project 2
Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria
Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda
A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
L9LS-R21 Interaction
Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines
Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso