Key Insights

Highlights

Success Rate

96% trial completion (above average)

Published Results

133 trials with published results (15%)

Research Maturity

670 completed trials (78% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

3.5%

30 terminated out of 860 trials

Success Rate

95.7%

+9.2% vs benchmark

Late-Stage Pipeline

27%

231 trials in Phase 3/4

Results Transparency

20%

133 of 670 completed with results

Key Signals

133 with results96% success30 terminated

Data Visualizations

Phase Distribution

719Total
Not Applicable (193)
Early P 1 (3)
P 1 (199)
P 2 (93)
P 3 (108)
P 4 (123)

Trial Status

Completed670
Unknown81
Terminated30
Withdrawn23
Recruiting22
Active Not Recruiting20

Trial Success Rate

95.7%

Benchmark: 86.5%

Based on 670 completed trials

Clinical Trials (860)

Showing 20 of 20 trials
NCT05891236Phase 1CompletedPrimary

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

NCT06735209Phase 1Active Not RecruitingPrimary

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

NCT05652504Phase 1SuspendedPrimary

Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)

NCT07060508Phase 2CompletedPrimary

L9LS in Women of Childbearing Potential in Mali

NCT06607003Phase 1RecruitingPrimary

Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

NCT05690841Phase 3Recruiting

FocaL Mass Drug Administration for Vivax Malaria Elimination

NCT02639299RecruitingPrimary

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

NCT04978272Phase 3Active Not RecruitingPrimary

Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)

NCT03937817Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

NCT01168271RecruitingPrimary

Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali

NCT07430592Phase 2Not Yet RecruitingPrimary

This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria

NCT02471378RecruitingPrimary

Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates

NCT07246525Phase 4Not Yet RecruitingPrimary

Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission

NCT04529434Not ApplicableCompletedPrimary

Star Homes Project 2

NCT03503058Phase 2CompletedPrimary

Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria

NCT07548021Phase 1Not Yet Recruiting

Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda

NCT06069544Phase 1CompletedPrimary

A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

NCT07208760Phase 2WithdrawnPrimary

L9LS-R21 Interaction

NCT05155579Phase 1CompletedPrimary

Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines

NCT04650815CompletedPrimary

Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso

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Research Network

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