Malaria
859
24
44
668
Key Insights
Highlights
Success Rate
96% trial completion (above average)
Published Results
131 trials with published results (15%)
Research Maturity
668 completed trials (78% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
3.5%
30 terminated out of 859 trials
95.7%
+9.2% vs benchmark
27%
231 trials in Phase 3/4
20%
131 of 668 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 668 completed trials
Clinical Trials (859)
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays
Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
First-in-Human PfSPZ-LARC2 Vaccination/CHMI
Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
L9LS-R21 Interaction
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina Faso
Net Transition Initiative: Efficacy of Two Next-generation Nets for Control of Malaria in Cote d'Ivoire
Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
R21/MM Dosing, Presentations, and Preservatives
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults
Pregnancy Registry in Mali
An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria
A Study Assessing the Safety, Efficacy, and Impact of GlaxoSmithKline Biologicals' RTS, S/AS01E Malaria Vaccine in Young Children Across Sub-Saharan Africa
This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria