NCT01158781

Brief Summary

The purpose of this study is to restore life role participation for those with TBI by customizing, applying, and testing integrated cognitive and motor training protocols that were successful in populations with impairments similar to TBI. The treatment protocols are based on principles of brain plasticity and re-learning, required to restore cognitive and motor function. The intervention targets an array of impairments that are obstacles to life role participation. These include cognitive attention and executive control; motor control for upper limb function; balance and gait; and cognitive executive control of simultaneous cognitive and motor tasks required by everyday tasks. The intervention utilizes training specificity, framing the intervention within functional task and life role activity component practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 13, 2009

Completed
9 months until next milestone

First Posted

Study publicly available on registry

July 8, 2010

Completed
1.8 years until next milestone

Study Start

First participant enrolled

May 1, 2012

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2017

Completed
Last Updated

March 26, 2019

Status Verified

March 1, 2019

Enrollment Period

5.4 years

First QC Date

October 13, 2009

Last Update Submit

March 23, 2019

Conditions

Keywords

TBImotor learningroboticsFunctional electrical stimulation

Outcome Measures

Primary Outcomes (1)

  • Berg Balance

    Balance function

    week 12

Study Arms (1)

gait, balance, arm function, cognition

EXPERIMENTAL

12 weeks of training for balance, gait, upper limb function, and cognition

Behavioral: Experimental: gait, balance, arm function, cognition

Interventions

12 weeks of training for balance, gait, upper limb function, and cognition, including functional electrical stimulation with surface electrodes, robotics, and motor learning

gait, balance, arm function, cognition

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Medically Stable
  • Age \> 18 years
  • Ability to walk at least with the minimum assistance of one person or an assistive device
  • At least 6 months post injury
  • Ability to follow 2 stage commands

You may not qualify if:

  • pacemaker
  • Acute medical conditions
  • potential subjects will undergo a screening evaluation to determine eligibility for study entry

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gainesville VA Medical Center

Gainesville, Florida, 32608, United States

Location

MeSH Terms

Conditions

Brain Injuries, Traumatic

Condition Hierarchy (Ancestors)

Brain InjuriesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemWounds and Injuries

Study Officials

  • Janis Daly, Ph.D., M.S.

    US Department of Veterans Affairs

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, Brain Rehabilitation Research Center

Study Record Dates

First Submitted

October 13, 2009

First Posted

July 8, 2010

Study Start

May 1, 2012

Primary Completion

October 1, 2017

Study Completion

October 1, 2017

Last Updated

March 26, 2019

Record last verified: 2019-03

Locations